نتایج جستجو برای: p32
تعداد نتایج: 796 فیلتر نتایج به سال:
We show that caspase-3 cleaves Cdc6 at D(290)/S and D(442)/G sites, producing p32-tCdc6 (truncated Cdc6) and p49-tCdc6, respectively, during etoposide- or tumor necrosis factor (TNF)-alpha-induced apoptosis. The expression of these tCdc6 proteins, p32- and p49-tCdc6, promotes etoposide-induced apoptosis. The expression of tCdc6 perturbs the loading of Mcm2 but not Orc2 onto chromatin and activa...
The reversibility of reaction (2) was discovered by Lardy and Ziegler (2), who showed that the failure of Meyerhof et al. (3) to demonstrate the backreaction with P32 was due to the absence of K ion. In the meantime it had been found by Boyer et al. (4) that K ion is indispensable for the transphosphorylation of phosphopyruvate with ADP. We have confirmed the results of Lardy and Ziegler, and h...
OR some time it has been generally considered that the production of F chromosomal aberrations in Tradescantia and many other materials is essentially independent of the wave length of the exciting radiation in the region shorter than 1.5 A. This view has not been seriously questioned in recent years and to date has remained one of the fundamental tenets of radiobiology. A number of isolated in...
BACKGROUND Retinopathy of prematurity (ROP) is a condition of abnormal retinal vascular development (RVD) in premature infants. Fluorescein angiography (FA) has depicted phases (early, mid, late, and mature) of RVD in oxygen-induced retinopathy (OIR) mice. We sought to establish the relationship between retinal structural and vascular changes using simultaneous FA and spectral domain optical co...
The toxic effects of morphine sulfate in the adult cerebral cortex and one-day neonatal cerebellum have been studied. This study was carried out to evaluate the effect of maternal morphine exposure during gestational and lactation period on the Purkinje cells and cerebellar cortical layer in 18- and 32-day-old mice offspring. Thirty female mice were randomly allocated into cases and controls. I...
Triple negative breast cancer (TNBC) is the deadliest form of breast cancer and its successful treatment critically depends on early diagnosis and therapy. The hyaluronic acid-binding p32 protein is overexpressed in TNBC, specifically in macrophages in hypoxic areas of the tumor. Here we used polyethylene glycol-polycaprolactone (PEG-PCL) polymersomes that were affinity targeted with the p32-bi...
Abstract Sheep pox is a highly contagious infectious viral disease (F/Poxviridae, G/ Capripoxvirus ), still causing economic damage in endemic zones like northern Africa, the Middle East, and many regions Asia. Nevertheless, clinical symptoms caused by sheep virus (SPPV) similar to those genetically related viruses, notably goat (GTPV) lumpy skin (LSDV). One of main objectives current study cha...
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