Testing of the hypothesis that good precision-recall performance can be based entirely on proximity relationships is a focus of current TREC work at ANU. PADRE's \Z-mode" method (based on proximity spans) of scoring relevance has been shown to produce reasonable results for hand-crafted queries in the Adhoc section. It is capable of producing equally good results in database merging and routing...

A high-resolution X-ray structure of an aquaporin has revealed water molecules bound within the transmembrane pore and provided new clues to the mechanisms of rapid water transport and high selectivity in this important class of membrane proteins.

form the results of the first randomized study comparing conventional chemotherapy plus novel agents to tandem high-dose melphalan and ASCT in 402 newly diagnosed MM patients. At the time of the report, with a short follow up, there was no significant difference in OS between the two groups, but PFS was significantly improved in the early HDT arm. Two other ongoing trials, one conducted by the ...

Vibrios are natural inhabitants of aquatic environments and form symbiotic or pathogenic relationships with eukaryotic hosts. Recent studies reveal that the ability of vibrios to form biofilms (i.e. matrix-enclosed, surface-associated communities) depends upon specific structural genes (flagella, pili and exopolysaccharide biosynthesis) and regulatory processes (two-component regulators, quorum...

Web applications have emerged as the primary means of access to vital and sensitive services such as online payment systems and databases storing personally identifiable information. Unfortunately, the need for ubiquitous and often anonymous access exposes web servers to adversaries. Indeed, network-borne zero-day attacks pose a critical and widespread threat to web servers that cannot be mitig...

The adage lex orandi, credendi, vivendi (or (con)vivendi) denotes causal interrelationships between worship, belief and life. Simply one affects the others as this forms foundation of doctrine and/or a moral However, if there are true relationships “as we worship” (lex orandi), “so believe” credendi), live” vivendi) then can also be understood as: vivendi), orandi). This leads o question: how d...