Background: Polyethylene glycol (PEG), an osmotic laxative, is a very potent inhibitor of colon cancer in rats. In a search for mechanisms, we tested the hypothesis that fecal bulking and moisture decreases colon carcinogenesis. We also looked for PEG effects on crypt cells in vivo. Methods: Fischer 344 rats (N=272) were given an injection of the colon carcinogen azoxymethane. They were then ra...

Wine has been part of the history mankind for millennia and is a very important product industry from an economic point view, being considered luxury product, which makes it susceptible to fraud adultery. The predisposition purchase new foods or products obtained in non-traditional way depends largely on individual, perception consequently, approach consumer development focused needed. In curre...

OBJECTIVE Polyethylene glycol (PEG), an osmotic laxative, is a potent inhibitor of colon cancer in rats. In a search for the underling mechanisms, the hypothesis that fecal bulking and moisture decrease colon carcinogenesis was tested. We also investigated the PEG effects on crypt cells in vivo. MATERIAL AND METHODS Fischer 344 rats (n=272) were injected with the colon carcinogen, azoxymethan...