abstractin the present work we set out to investigate the neuroprotective effects of noscapine (0.5-2 µm) in presence of d-glucose on primary murine foetal cortical neurons after oxygen–glucose deprivation/24 hrs recovery. cell viability, nitric oxide production and intracellular calcium ([ca2+]i) levels were evaluated by mtt assay, the modified griess method and fura-2 respectively. 25 and 100...

monascus purpureus is a fungus that had been cultured on the rice in eastern asian countries since thousands years ago and used as a food for long years. the fungus produces very valuable metabolites with polyketide structure. the most important metabolite is monacolin k, lovastatin or competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme a reductase (an affective enzyme in cholesterol s...

brucellosis is an infectious disease with high impact on innate immune responses which is induced partly by its dna. in the present study the potential differences of wild type and patients isolates versus attenuated vaccine strains in terms of cytokines, ros and no induction on murine splenocytes and peritoneal macrophages were investigated. this panel varied in base composition and included d...

metals can cause oxidative stress by increasing the formation of reactive oxygen species (ros), which make antioxidants incapable of defiance against growing amounts of free radicals. metal toxicity is related to their oxidative state and reactivity with other compounds. however, several reports about metals have been published in the recent years. mitochondria, as a site of cellular oxygen con...

plants face many biotic and abiotic stresses at the same time during their growth under field conditions. plants responses toward combined stresses are often more complex than their responses to one type of stress in a way that the results of these responses are called as cross tolerance. this mixture of stresses activates specific models of gene expression that causes special signaling network...

objective: ageing of the stored seed is a natural phenomenon and the seeds tend to lose viability even under ideal storage conditions. accelerated ageing has been recognized as a good predictor of the storability of seed lots. aged seeds show decreased vigor and produce weak seedlings that are unable to survive once reintroduced into a habitat. the characteristics of the chemical composition of...

background & aim : pulse oximetry is a frequently used and standard non-invasive method for monitoring oxygen (o2)-saturation in blood. many factors including dark skin and pigmentation may effect on rate of saturation of the blood oxygen absorbed by pulse oximetry. the effect of nail polish and/or henna color on blood oxygen has not been yet identified and the present study has been carried ou...

the influence of initial moisture content on wood decay at different levels of atmospheric oxygen concentration was studied. three fungi, coriolus versicolor (c. versicolor) a white rot, coniophora puteana (c. puteana) a brown rot, and chaetomium globosum (c. globosum) a soft rot, were chosen. the mycelia of the fungi were inoculated in to mini blocks of fagus sylvatica (beech) and pinus sy...