BACKGROUND When fructose is ingested together with glucose (GLUFRU) during exercise, plasma lactate and exogenous carbohydrate oxidation rates are higher than with glucose alone. OBJECTIVE The objective was to investigate to what extent GLUFRU increased lactate kinetics and oxidation rate and gluconeogenesis from lactate (GNG(L)) and from fructose (GNG(F)). DESIGN Seven endurance-trained me...

The oxidative metabolism of irbesartan, a new nonpeptide angiotensin II receptor antagonist, was investigated on 12 human fully characterized hepatic microsomes and purified cytochrome P-450 (CYP) isoforms. After incubation of microsomes with irbesartan and NADPH, four main hydroxy metabolites were formed, as confirmed by liquid chromatography-mass spectrometry analysis. Irbesartan oxidation fo...

The oxidation behavior of fully dense Ti2SC was studied thermogravimetrically in air in the 500–800°C temperature range. The oxidation product was a single-layer of rutile in all cases. At 800°C, the oxide layer was not protective and the oxidation kinetics were rapid. At 600 and 700°C, and up to ~50 h, the kinetics were parabolic before they became linear. It was only at 500°C that the weight ...

The WTaNbTiAl alloy demonstrated excellent oxidation resistance with a 31.83 mg/cm2 of specific mass gain after 48 h at 1000 °C in the air environment. Based on multi-scale microstructural characterizations, diffusion-controlled three-layers oxide scale model was proposed to explain kinetics this RHEA. In addition, thermodynamic calculation results shed light formation mechanism oxides based st...

Gallic acid-functionalized materials possess superior tissue-adhesive, antioxidant, and immunomodulatory properties due to the lower pKa faster oxidation kinetics, making them dopamine derivatives for biomedical applications.

Results on isothermal oxidation at 873 K for 90 h of Al–Pt coatings on Ti6242 coupons are reported. These coatings were obtained by low temperature, low pressure metalorganic chemical vapor deposition using Me3(MeCp)Pt(VI) and dimethylethylamine alane. Three coating architectures were investigated, namely pure Al, Pt and Al sequential sublayers, and co-deposited Al and Pt. Oxidation kinetics re...

Changes in the kinetics of leucine in the mammary gland were examined in four lactating goats (25, 38, 45, and 135 DIM) that were given an i.v. infusion of a mixture of 18 AA, not including leucine, to alter the availability of leucine to the gland relative to other AA. Arteriovenous monitoring of [1-13C]leucine kinetics across one-half of the mammary gland was conducted on the last day (d 6 or...

CONTEXT Long-term hormone replacement therapy (HRT) with estradiol (E(2)) is associated with an altered lipid profile including unfavorable increases in triglyceride (TG) concentrations and augmented hepatic very low-density lipoprotein (VLDL)-TG production. There are indications that this effect of estrogens may be immediate. OBJECTIVE To study the in vivo effect of a single dose of E(2) on ...

Low temperature oxidation in the gas and condensed phases has been the subject of experimental investigations for many decades owing to applications in many areas of practical significance like thermal stability, combustion, atmospheric chemistry and industrial syntheses. Owing to several practical limitations it has proven difficult to understand these processes at a mechanistic level from exp...

This work presents the results of the theoretical investigations on autoxidation process of diethyl ether (DEE), a chemical largely used as solvent in laboratories and considered to be responsible for various accidents. Based on Density Functional Theory (DFT) calculations, the aims of this study were the identification of all the most probable reaction paths involved in DEE oxidation (at ambie...