In this study a cobalt(II) complex of quercetin was synthetized in the solid state with general formula Co(C15H9O7)2∙2H2O. The FT-IR, elemental analysis, and UV/Vis methods were used to composition water solution. anti-/pro-oxidant activity Co(II) studied by means spectrophotometric DPPH (2,2-diphenyl-1-picrylhydrazyl), FRAP (ferric reducing antioxidant activity) Trolox oxidation assays. cytoto...

Lack of physical activity, smoking and/or inappropriate diet can contribute to the increase of oxidative stress, in turn affecting the pathophysiology of cardiovascular diseases. Strong anti-oxidant properties of plant polyphenolic compounds might underlie their cardioprotective activity. This paper reviews recent findings on the anti-oxidant activity of plant leaf extracts and emphasizes their...

Tephrosia purpurea is a species of flowering plant in the pea family, Fabaceae, which has a pantropical distribution. According to Ayurveda, the plant is anthelmintic, alexiteric, restorative, and antipyretic; it is used in the treatment of leprosy, ulcers, asthma, and tumors, as well as diseases of the liver, spleen, heart, and blood. A decoction of the roots is given in dyspepsia, diarrhea, r...

the aim of this reaserch was evaluathng the aluminum-sulphate concentration levels in preserved solution with stem recutting on longevity of rosa hybrida cv. varlon cut flowers. the investigation was conducted in horticultural lab,agriculturalcollege,zanjanuniversity. rose cut stems were produced in greenhouse from biennial mother stocks and were placed under the treatment of aluminum-sulphate ...

Phagocyte-mediated oxidant damage to vascular endothelium is likely involved in various vasculopathies including atherosclerosis and pulmonary leak syndromes such as adult respiratory distress syndrome. We have shown that heme, a hydrophobic iron chelate, is rapidly incorporated into endothelial cells where, after as little as 1 h, it markedly aggravates cytotoxicity engendered by polymorphonuc...

Oxidant-induced cell injury has been implicated in the pathogenesis of several forms of acute renal failure. The present studies examined whether activation of poly(ADP-ribose)polymerase (PARP) by oxidant-induced DNA damage contributes to oxidant injury of renal epithelial cells. H2O2exposure resulted in an increase in PARP activity and decreases in cell ATP and NAD content. These changes were ...

Dirithromycin is a 14-membered macrolide antibiotic, well known to yield high intragranulocytic levels after several hour exposure. We chose therefore to investigate oxidative metabolism after prolonged incubation periods with neutrophils. Neutrophil generation of reactive oxygen species, represented by superoxide anion, was assessed after fMLP or Staphylococcus aureus-induced activation of the...

Oxidative stress can contribute to the multifactorial etiology of whole body and skeletal muscle insulin resistance. No investigation has directly assessed the effect of an in vitro oxidant stress on insulin action in intact mammalian skeletal muscle. Therefore, the purpose of the present study was to characterize the molecular actions of a low-grade oxidant stress (H(2)O(2)) on insulin signali...