PURPOSE We aimed to estimate the prevalence of overactive bladder (OAB) in Korea, to assess the variation in prevalence by sex and age, and to measure the impact of OAB on quality of life. METHODS A population-based, cross-sectional telephone survey was conducted between April and June 2010 with a questionnaire regarding the prevalence of OAB, demographics, and the impact of OAB on quality of...

PURPOSE The goal of this study was to compare the International Prostate Symptom Storage Subscore (IPSS-s) and the overactive bladder symptom score (OABSS) as tools for assessing the symptoms of overactive bladder (OAB). METHODS A cross-sectional study was conducted of a sample of 1,341 patients aged 50 years and older with lower urinary tract complaints who had undergone a medical examinatio...

PURPOSE Bladder outlet obstruction (BOO) causes storage and voiding dysfunction in the lower urinary tract. We investigated the expression of transient receptor potential cation channel subfamily M member 8 (TRPM8) to evaluate the relationship between TRPM8 expression and overactive bladder (OAB) in a rat model of BOO. METHODS Fifty female Sprague-Dawley rats were divided into 4 groups; norma...

We aimed to estimate the prevalence of overactive bladder (OAB) in South of China, to assess the variation in prevalence by sex and age, and to measure the impact of OAB on quality of life. A population-based, cross-sectional telephone survey was conducted with a questionnaire regarding the prevalence of OAB, demographics, and the impact of OAB on quality of life. A geographically stratified ra...

PURPOSE Male overactive bladder (OAB) may be caused by prostatic pathologies such as bladder outlet obstruction (BOO). Intravesical prostatic protrusion (IPP) has been found to correlate with BOO and acute urinary retention. We investigated the interrelation between male OAB symptoms and IPP for estimating anatomical changes to the prostate. MATERIALS AND METHODS We assessed 179 consecutive m...

UNLABELLED Overactive Bladder Syndrome (OAB) is defined by the ICS (International Continence Society) as urinary urgency, with or without urgency incontinence and frequently associated with increase of frequency and nocturia. PURPOSE The aim of the study was to establish a correlation between OAB symptoms and Age in women aged 20-45. MATERIALS AND METHODS We interviewed 1050 women aged 20-4...

The ankyrin-repeat transient receptor potential 1 (TRPA1) has been implicated in pathological conditions of the bladder, but its role in overactive bladder (OAB) following spinal cord injury (SCI) remains unknown. In this study, using a rat SCI model, we assessed the relevance of TRPA1 in OAB induced by SCI. SCI resulted in tissue damage, inflammation, and changes in bladder contractility and i...

We compared the effects of bladder training and/or tolterodine as first line treatment in female patients with overactive bladder (OAB). One hundred and thirty-nine female patients with OAB were randomized to treatment with bladder training (BT), tolterodine (To, 2 mg twice daily) or both (Co) for 12 weeks. Treatment efficacy was measured by micturition diary, urgency scores and patients' subje...

AIMS To investigate the association of both the urodynamic profiles and patterns of detrusor overactivity (DO) with the severity of the symptoms related to overactive bladder (OAB) in men with benign prostatic enlargement (BPE) associated with DO. METHODS A total of 777 men with symptomatic BPE who had undergone transurethral resection of the prostate (TURP) were retrospectively analyzed. All...

Succinate, an intermediate metabolite of the Krebs cycle, can alter metabolomics response to certain drugs and controls array molecular responses in urothelium through activation its receptor, G-protein coupled receptor 91 (GPR91). Mirabegron, a β3-adrenergic (β3-AR) agonist used treat overactive bladder syndrome (OAB), increases intracellular cAMP detrusor smooth muscle cells (SM...