The ovarian hyperstimulation syndrome (OHSS) is a consequence of superovulation therapy for assisted conception procedures. This potentiallyfatal condition is avoidable by the judicious use of gonadotropins and carefulmonitoring of stimulation regimens. Women who are at particular risk ofdeveloping the syndrome include those who have polycystic ovaries and thosewho are young (under 30 years). W...

I read the recent publication on ovarian hyperstimulation syndrome (OHSS) with great interest.(1) Rajesh et al concluded that “gonadotropin doses at stimulation should start at 150 iu or less in women below 35 years of age, with a step-up of 37.5 iu, as necessary.(1)” There are some points to note about this research. First, as a retrospective study, it might not be possible to control the conf...

BACKGROUND Repeated in vitro Fertilization (IVF) failure together with Ovarian Hyperstimulation Syndrome (OHSS) is one of the distressing situations leading couples to search for alternative treatment options. For such patients with Polycystic Ovarian Syndrome (PCOS) who have experienced Ovarian Hyperstimulation Syndrome, mild ovarian stimulation with in vitro oocyte maturation could be a promi...

Ovarian hyperstimulation syndrome (OHSS) is a potentially life-threatening complication of pharmacological ovarian stimulation. It is seen in approximately 2 % of all IVF cycles. The prevalence of moderate to severe OHSS ranges from 1 to 10 % in major IVF programs. Severe forms complicate 1 % of IVF cycles and are characterized by massive ovarian enlargement together with a fluid shift into ext...

BACKGROUND There is growing and consistent evidence showing that ovarian reserve is affected following surgical excision of ovarian endometriomas. Of particular concern is the risk of severe ovarian damage leading to unresponsiveness to ovarian hyperstimulation. In this study, we aimed to determine the rate of this complication. METHODS Ninety-three women underwent surgery for monolateral end...

A 19-year-old thalassemic woman had tissue from one of her ovaries cryopreserved prior to bone marrow transplantation, total body irradiation and sterilizing chemotherapy. As expected, premature ovarian failure resulted from this treatment. Transplantation of her thawed ovarian tissue resulted in return of menstrual cycling and the patient then underwent several IVF cycles. The patient, however...

In a prospective randomized trial comparing efficacy of double over single intrauterine insemination (IUI), 160 couples with unexplained infertility underwent controlled ovarian hyperstimulation and IUI. The pregnancy rates were similar and statistically not different between groups, suggesting that double IUI added no advantage over single IUI.

This report describes two cases that developed moderate ovarian hyperstimulation syndrome (OHSS) without evidence of haemoconcentration. Both patients developed serious cerebrovascular thrombosis resulting in hemiparesis, and recovered after treatment with anticoagulants. This report emphasizes that other factors may contribute to vascular thrombosis, and illustrates that cerebrovascular accide...

Unusual cause of pleural effusion: ovarian hyperstimulation syndrome N. Srivali, C. Thongprayoon, W. Cheungpasitporn, P. Ungprasert and S.M. Caples From the Department of Pulmonary and Critical Care, Mayo Clinic, Rochester, MN, USA, Department of Internal Medicine, Bassett Medical Center, Cooperstown, NY, USA, Department of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA and Depart...

We report a combined intra-uterine and tubal pregnancy associated with mild ovarian hyperstimulation syndrome (OHSS) following ovulation induction by clomiphene. The diagnosis of ectopic pregnancy was originally missed until rupture occurred. OHSS confused the clinical picture, the important diagnostic feature being the fall in the haemoglobin concentration. The patient had a left partial salpi...