Percutaneous septal ablation has emerged as a less invasive treatment of symptomatic patients with hypertrophic obstructive cardiomyopathy (HOCM). In the past decade, the availability of this sophisticated technique has revived the interest of cardiologists in left ventricular outflow tract obstruction, which led to the recognition that most patients with HCM have the obstructive type. Follow-u...

A 63-year old man with a significant left ventricular outflow obstruction due to an aberrant sub-valvular mitral tissue (not characteristic of a classical subaortic web; Fig. 1a and b), underwent resection of the mass and septal myectomy through a trans-aortic approach (Fig. 1c). Postoperative echocardiography demonstrated a reduction in the subaortic resting gradient of 70%, with no evidence o...

We report the case of a 33-year-old male with primary seminoma of the anterior mediastinum with initial clinical manifestations suggestive of heart disease.

Hypertrophic cardiomyopathy is a fascinating disease of marked heterogeneity. Hypertrophic cardiomyopathy was originally characterized by massive myocardial hypertrophy in the absence of known etiology, a dynamic left ventricular outflow obstruction, and increased risk of sudden death. It is now well accepted that multiple mutations in genes encoding for the cardiac sarcomere are responsible fo...

Most model-based diagnosis systems, such as GDE and Sherlock, have concerned discrete, static systems such as logic circuits and use simple constraint propagation to detect inconsistencies. However, sophisticated systems such as QSIM and QPE have been developed for qualitative modeling and simulation of continuous dynamic systems. We present an integration of these two lines of research as impl...

This case describes a successful percutaneous stent implantation to critical stenosis of the right ventricle outflow tract in a female neonate with tetralogy of Fallot. At the time of the procedure she had poor development of the pulmonary arteries (McGoon and Nakata index 1.45 and 120, respectively). Stent implantation ensured an immediate increase in oxygen saturation level, and the physiolog...

A patient who had had successful operation for a common atrium subsequently developed subaortic stenosis and regurgitation several years later. The diagnosis of subaortic lesion was confirmed by echocardiography. This case shows that the left ventricular outflow tract gradient should be measured before operation for common atrium and that after operation such cases should be examined by cross s...

A patient who had had successful operation for a common atrium subsequently developed subaortic stenosis and regurgitation several years later. The diagnosis of subaortic lesion was confirmed by echocardiography. This case shows that the left ventricular outflow tract gradient should be measured before operation for common atrium and that after operation such cases should be examined by cross s...

Various treatment modalities have been introduced to reduce the subaortic pressure gradient in patients with obstructive hypertrophic cardiomyopathy, including pacemaker insertion. Complete ventricular capture during pacing is essential and requires optimization of the atrioventricular interval (AVI). In this study, a protocol using echocardiographic examination assessing the changes in the lef...

The central region of the molecular outflow in the R Coronae Australis cloud was mapped in HCO+(J = 1 − 0), H13CO+(J = 1 − 0), HCO+(J = 3 − 2) and C18O(J = 2 − 1) with the SEST. In addition to the maps, selected positions were observed in SiO(J = 2 − 1, v = 0). The observations reveal a complex system consisting of a dense core, a rotating molecular disk around the infrared source IRS 7 and a d...