The well known monopole solution of Barriola and Vilenkin (BV) resulting from the breaking of a global SO(3) symmetry is extended in general relativity along with a zero mass scalar field and also in Brans-Dicke(BD) theory of gravity.In the case of BD theory , the behaviour of spacetime and other variables such as BD scalar field and the monopole energy density have been studied numerically.For...

BACKGROUND Aortic valve (AV) calcification preferentially occurs on the fibrosa side while the ventricularis side remains relatively unaffected. Here, we tested the hypothesis that side-dependent activation of bone morphogenic protein (BMP) pathway in the endothelium of the ventricularis and fibrosa is associated with human AV calcification. METHODS AND RESULTS Human calcified AVs obtained fr...

A child with a giant cell lesion (brown tumor) associated with secondary hyperparathyroidism due to chronic renal failure was reported. The patient presented at age 6 years, 5 months with swelling in the right mandible that was biopsied and diagnosed histologically as a giant cell lesion. The patient received a successful kidney transplant 8 months later and the giant cell lesion resolved durin...

Nine patients with symptomatic and severe fibrous dysplasia were treated with intravenous pamidronate (60 mg per day over 3 days every sixth month), and were followed up for 18-48 months. The major effect was decreased bone pain (complete remission in 12 of 14 sites). Radiological changes were seen in four patients, with thickening of cortices, refilling of osteolytic lesions, or both. The init...

3. Fang GD, Yu VL, Vickers RM. Disease due to Legionellaceae (other than Legionella pneumophila): historical, microbiological, clinical and epidemiological review. Medicine (Baltimore). 1989;68:116–39. 4. Domínguez J, Galí N, Blanco S, Pedroso P, Prat C, Matas L, et al. Assessment of a new test to detect Legionella urinary antigen for the diagnosis of Legionnaire’s Disease. Diagn Microbiol Infe...

Here we report a 65-year-old woman with multiple brown tumors and renal stones secondary to primary hyperparathyroidism. This case highlights the need for early recognition of parathyroid hyperactivity.

The proliferative potential of a spinal nephroblastoma was studied in a young dog. A 4-month-old, female golden retriever showed developing deterioration in her gait and subsequent paralysis of her hind legs. At necropsy, a well-demarcated grayish brown tumor mass was found in the lumbar spinal cord segments between L2 and L3. Histologically, a blastemal cell tumor with a tubule- or glomeruli-l...

Brown tumors are giant cell focal lesion that arises as a result of abnormal bone metabolism in patients with hyperparathyroidism (HPT). The lesions localize in areas of extensive bone resorption, which is replaced by fibrovascular tissue and giant cells with abundant deposits hemorrhage and hemosiderin. A rare case of brown tumor of mandible in a 22-year-old woman is reported here. This case e...

The assessment of flicker fusion frequency (FFF), the stimulus frequency at which a flickering light stimulus can no longer be resolved and appears continuous, and critical flicker fusion frequency (CFF; the highest frequency at any light intensity that an observer can resolve flicker) are useful methods for comparing temporal resolution capabilities between animals. Behavioural experiments hav...