VEGF is a well known angiogenic peptide which has been shown to be central to endochondral ossification. Secondary fracture healing involves a combination of intramembranous and endochondral ossification. VEGF has been recently shown to be chemotactic for osteoblasts [1] and chondroclasts and central to endochondral ossification [2]. Fracture healing physiology involves a complex cascade of num...

Ossification of the stylohyoid ligament is very common in the Caucasian population. More than 9000 descriptions of apparently isolated case reports on PubMed have been cited over the last 20 years, often associated with an incidental finding on imaging after neck trauma. No cases of familial ossification have been described. We document a family with several affected members, each with an ossif...

Ossification of the tentorium cerebelli over the trigeminal notch is rare, but it may cause compression of the trigeminal nerve, leading to trigeminal neuralgia (TN). We were unable to find any previously reported cases with radiological evaluation, although we did find one case with surgically proven ossification of the tentorium cerebelli. Here, we present a case of TN caused by tentorial oss...

Albright"s hereditary osteodystrophy (AHO) is a complex genetic disorder characterized by brachydactyly, gonadotropin resistance, hypothyroidism, pseudohypoparathyroid syndrome and heterotopic ossification. Heterotopic ossification rarely occurs in the maxillofacial region. In this article, we present such a case, describe the etiology, characteristics and treatment of AHO and suggest a potenti...

background: this study addresses the null hypothesis that there is no expansion of heterotopic ossification (ho) in the elbow beyond what can be seen early on.   methods: the area of ho was measured on lateral radiographs of 38 consecutive patients that had operative treatment of ho between 2000 and 2013. measurements from radiographs obtained between 3 to 7 weeks were compared to measurements ...

INTRODUCTION Heterotopic ossification is a rare complication of musculoskeletal injuries, characterized by bone growth in soft tissues. Percutaneous antegrade intramedullary nailing represents the 'gold standard' for the treatment of femur shaft fractures. Minor bone growth is frequently seen around the proximal end of reamed femoral nails (so-called 'callus caps'), which are asymptomatic and l...

BACKGROUND It has been our experience that ossification occurs adjacent to anterior cervical plates. Our hypothesis was that the closer the plate is to the adjacent disc space, the greater the ossification. METHODS We retrospectively reviewed the lateral radiographs of the cervical spine of 118 patients who had a solid fusion following an anterior cervical arthrodesis with a plate for the tre...