ever since psychological issues became a focus of attention in oncology, many studies have been conducted to quantitatively address the impaired sexual function among women diagnosed with breast cancer; however, we lack qualitative measurement of sexual dysfunction and patients’ needs. conducting research about “sexual function in breast cancer patients” in 2009 at the tehran cancer institute s...

background: bladder cancer is one of the most common cancers in the world with considerably higher frequency among men than women. treatment of the disease is possible according to early diagnosis, so identifying useful markers is very important. lsinct5 (long stress-induced non-coding transcript 5) is a stress-regulated lncrna involved in response to oxidative stress, also in cell proliferatio...

background: inhibin is a dimeric glycoprotein that has a depressive effect on the anterior hypophyse secretion. the level of this tumor marker is undetectable in menopause women. in patients with gynecological cancer, especially granulosa and epidermal-type (mucinous), ovarian cancers considerable increase in the serum level of inhibin has been reported. the increased level of inhibin has been ...

background: cancer is one of the three health issues of the society and the third cause of mortality in iran. food habits play a significant role in preventing cancer. the present study therefore, was carried out to assess food habits of tehran citizens for cancer prevention. methods: this study is a cross- sectional study was conducted with a sample of 2500 tehran citizens who were recruited t...

background : breast cancer is a complicated disease and has various clinical manifestations and prognosis. the aim of this study is to make a breast cancer model suitable for basic, preclinical and clinical studies. materials and methods: five virgin bulb/c mice aged 6 weeks and spontaneous murine mammary adenocarcinoma cells (mmac) were used. after anesthesia induction, 1-3 million of mmacs we...

background: the her-2/neu gene is located on chromosome 17q21 and encodes a 185-kda transmembrane glycoprotein with tyrosine kinase activity reported to be released in soluble form in various malignancies. objective: to evaluate the clinical significance of soluble her-2/neu as a diagnostic marker in lung cancer. methods: serum levels of soluble her-2/neu were measured in 43 patients with lung ...

background: it is now well-demonstrated that histone demethylases play an important role in developmental controls, cell-fate decisions, and a variety of diseases such as cancer. lysine-specific demethylase 5d (kdm5d) is a male-specific histone demethylase that specifically demethylates di- and tri-methyl h3k4 at the start site of active genes. in this light, the aim of this study was to invest...

background: colorectal cancer (crc) is the third most common malignancy in iran. limited data are available on knowledge and barriers in regard to crc and screening tests in iran. the aim of  the study was to characterize knowledge, practice, and barriers toward crc and its screening tests among an iranian at‑risk population. methods: this cross‑sectional study was conducted with participation ...

background: today, cancer is one of the major health problems worldwide, and the importance of this disease in our country is growing. this cancer is the third cause of death and accounts for the second largest group of non-transmissible chronic diseases. colorectal cancer is the most common gastrointestinal cancer and includes 10%  of deaths from cancer around the world. different genetic and ...