The initiation and maintenance of physiological and pathophysiological oscillatory activity depends on the synaptic interactions within neuronal networks. We studied the mechanisms underlying evoked transient network oscillation in acute slices of the adolescent rat somatosensory cortex and modeled its underpinning mechanisms. Oscillations were evoked by brief spatially distributed noisy extrac...

We study the semi-classical behavior of the spectral function of the Schrödinger operator with short range potential. We prove that the spectral function is a semiclassical Fourier integral operator quantizing the forward and backward Hamiltonian flow relations of the system. Under a certain geometric condition we explicitly compute the phase in an oscillatory integral representation of the spe...

BACKGROUND High-frequency oscillatory ventilation is an alternative ventilation mode that improves oxygenation in trauma patients in whom conventional ventilation strategies have been unsuccessful. OBJECTIVE To evaluate the effect of high-frequency oscillatory ventilation on oxygenation, survival, and parameters predictive of survival in trauma patients. METHODS A retrospective case series ...

An excitable medium is a nonlinear dissipative dynamical system able to sustain undamped wave propagation. Examples of excitable media include cardiac tissue and neural media. This thesis investigates a class of novel dynamical phenomena in excitable media, known collectively as oscillatory waves. The examples of oscillatory waves considered here are Tango waves, breathers and pulse generators....

In many biological systems, the electrical coupling of nonoscillating cells generates synchronized membrane potential oscillations. This work describes a dynamical mechanism in which the electrical coupling of identical nonoscillating cells destabilizes the homogeneous fixed point and leads to network oscillations via a Hopf bifurcation. Each cell is described by a passive membrane potential an...