نتایج جستجو برای: organophosphorus pesticides

تعداد نتایج: 21436  

2017
Lisa Chedik Dominique Mias-Lucquin Arnaud Bruyere Olivier Fardel

Intestinal absorption and brain permeation constitute key parameters of toxicokinetics for pesticides, conditioning their toxicity, including neurotoxicity. However, they remain poorly characterized in humans. The present study was therefore designed to evaluate human intestine and brain permeation for a large set of pesticides (n = 338) belonging to various chemical classes, using an in silico...

Journal: :iranian journal of toxicology 0
neeraj kumar department of biotechnology, kurukshetra university kurukshetra, haryana, india. anita yadav department of biotechnology, kurukshetra university kurukshetra, haryana, india. sachin gulati department of biotechnology, kurukshetra university kurukshetra, haryana, india. kanu priya department of biotechnology, kurukshetra university kurukshetra, haryana, india. neeraj aggarwal department of microbiology, kurukshetra university kurukshetra, haryana, india. ranjan gupta department of biochemistry, kurukshetra university kurukshetra, haryana, india.

background: organophosphorus pesticides has been widely used in agriculture fields to control various crop insects and their extensive use pose human life at threat because of their adverse effects on human health. in this study, we checked the effects of gst polymorphism on ameliorative effect of curcumin and carvacrol against dna damages. methods: comet assay was used to assess the dna damage...

Journal: :BMJ clinical evidence 2011
Peter G Blain

INTRODUCTION Acetylcholinesterase inhibition by organophosphorus pesticides or organophosphate nerve agents can cause acute parasympathetic system dysfunction, muscle weakness, seizures, coma, and respiratory failure. Prognosis depends on the dose and relative toxicity of the specific compound, as well as pharmacokinetic factors. METHODS AND OUTCOMES We conducted a systematic review and aimed...

Journal: :Toxicology 2008
Steven B Bird Tara D Sutherland Chip Gresham John Oakeshott Colin Scott Michael Eddleston

Organophosphorus (OP) pesticides poison more than 3,000,000 people every year in the developing world, mostly through intentional self-poisoning. Advances in medical therapy for OP poisoning have lagged, and current treatment is not highly effective with mortality of up to 40% in even the most advanced Western medical facilities. Administration of a broadly active bacterial OP hydrolase to pati...

Journal: :International journal of occupational medicine and environmental health 2004
Maciej Tarkowski Waldemar Lutz Sarah Birindelli

Clinical and basic mechanism observations reveal interactions between neural and immune systems. These two systems create a complex network for recognizing danger to the host and its protection from outside pathogenic elements as well as from inside overreactions of inflammatory character. Here, we review the interactions of these two systems in relation to the effects of pesticides that clearl...

2012
Hadi Dehghani

In this work, elimination two types of organophosphorus pesticides, diazinon and malathion spiked in aqueous solution by ultrasonic irradiation was investigated. Six different initial concentrations of diazinon and malathion (100, 300, 500, 200, 400, and 600 μg/L respectively) at different pH (3, 7, 9) and time (30, 45, 60, 90, 105 min) were investigated. Results showed that diazinon and malath...

2010
Sherine O. Obare Chandrima De Wen Guo Tajay L. Haywood Tova A. Samuels Clara P. Adams Noah O. Masika Desmond H. Murray Ginger A. Anderson Keith Campbell Kenneth Fletcher

Many organophosphorus (OP) based compounds are highly toxic and powerful inhibitors of cholinesterases that generate serious environmental and human health concerns. Organothiophosphates with a thiophosphoryl (P=S) functional group constitute a broad class of these widely used pesticides. They are related to the more reactive phosphoryl (P=O) organophosphates, which include very lethal nerve ag...

2017
Jenna L. Gibbs Michael G. Yost Maria Negrete Richard A. Fenske

BACKGROUND Recent studies have highlighted the increased potency of oxygen analogs of organophosphorus pesticides. These pesticides and oxygen analogs have previously been identified in the atmosphere following spray applications in the states of California and Washington. OBJECTIVES We used two passive sampling methods to measure levels of the ollowing organophosphorus pesticides: chlorpyrif...

Journal: :International Journal of Chemical Engineering 2022

Pesticides are indispensable in today’s agriculture. Methyl-parathion hydrolase (MPH, E.C.3.1.8.1) could hydrolyze organophosphorus pesticides, including methyl-parathion. MPH rehabilitate soil and water resources contaminated by pesticides. However, natural MPHs generally exhibited a low tolerance to high temperatures catalytic efficiency. In this study, we improved the efficiency toward methy...

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