The large dynamic range of gene expression changes accompanying floral organ abscission can be explained by a molecular positive feedback loop that regulates the process. In short, a mitogen-activated protein kinase (MAPK) cascade, positioned genetically downstream from the abscission receptor HAESA (HAE), phosphorylates the transcription factor, AGAMOUS-like 15 (AGL15), allowing HAE to be expr...

Two otherwise healthy middle-aged males presented with persistent abdominal and lower- back pain, progressive weakness, paraesthesias, fatigue and weight loss over 8-12 months. Extensive work-up failed to localize organ pathology. Both men, strongly aware of the nutritional benefits of fish had a diet dedicated of canned and fresh fish. Raised blood mercury levels confirmed clinical suspicion a...

We characterized the first POU-homeoprotein in a crustacean (designated APH-1 for Artemia POU-Homeoprotein, EMBL Y15070). The amino acid sequence of the APH-1 POU-domain is identical, except for two residues, to that of the two class III POU proteins Cf1-a (Drosophila) and POU-M1 (Bombyx mori). Southern blot analysis suggests that crustaceans have only one class III POU gene. RT-PCR and whole-m...

Criteria are presented by which analytical methods may be judged to have been validated for the determination of pesticide residues. All stages of analysis are addressed, from initial preparation of samples to the production of results, but with a focus on simplicity and cost-effectiveness of the requirements. Criteria are provided for both quantitative and qualitative (screening) methods and t...

BACKGROUND Women living in agricultural areas may experience high pesticide exposures compared with women in urban or suburban areas because of their proximity to farm activities. OBJECTIVE Our objective was to review the evidence in the published literature for the contribution of nonoccupational pathways of pesticide exposure in women living in North American agricultural areas. METHODS W...

When environmentalists talk about pesticide exposure, they are usually referring to possible residue in our food. In fact, food is only one of many potential sources of pesticide residue in our environment. Both farmers and consumers, especially parents with small children, will benefit from the "risk cup" assessment of pesticide levels in our daily lives from ALL sources — not just agriculture...

Penicillin is one of the most commonly detected drug residues in tissues and milk, and is the antimicrobial for which information is most often sought through FARAD.

Chairman: J. A. R. BATES (UK); Secretary: R. GREENHALGH (Canada); Titular Members: N. AHARONSON (Israel); A. AMBRUS (Hungary); S. GORBACH (FRG); W. KLEIN (FRG); Associate Members: J. DESMORAS (France); H. 0. ESSER (Switzerland); L. A. GOLOVLEVA (USSR); R. J. HEMINGWAY (UK); R. HOLLINGWORTH (USA); N. KURIHARA (Japan); W. B. NEELY (USA); S. OTTO (FRG); T. R. ROBERTS (UK); J. SEIBER (USA); D. B. S...

[This corrects the article DOI: 10.1371/journal.pone.0077550.].

Cyprodinil is among the most common agrochemical residues found in highly perishable fruits, such as strawberries. In the present study, high-affinity monoclonal antibodies to this anilinopyrimidine fungicide were raised for the first time with the aim to produce valuable immunochemical analytical assays. Cyprodinil bioconjugates and the generated novel monoclonal antibodies were employed for s...