Porokeratosis refers to a group of hereditary or acquired disorders of epidermal keratinization and is characterized histologically by the presence of a cornoid lamella. The clinical variant referred to as disseminated superficial porokeratosis has been described in the literature in association with immunosuppressive conditions that include organ transplant, infections and immunosuppressive tr...

vitamin e is a potent reactive oxygen metabolites (rom) scavenger. it is a lipid-soluble vitamin and its main function is to protect polyunsaturated fatty acids against oxidative stress. twenty-five mechanically ventilated intensive care unit (icu) adult patients participated in a prospective randomized clinical trial receiving either placebo (10 patients) or 3 im doses (1000 iu each) of vitami...

Introduction For locally advanced-stage laryngeal and hypopharyngeal cancer, the total laryngectomy or laryngopharyngectomy can be an option for primary treatment. This is indicated when a partial resection not achievable while obtaining organ function preservation of its through radiotherapy possible.

The process of organ positioning has been addressed, using the pin-formed 1 (pin1) mutant as a tool. PIN1 is a transmembrane protein involved in auxin transport in Arabidopsis. Loss of function severely affects organ initiation, and pin1 mutants are characterised by an inflorescence meristem that does not initiate any flowers, resulting in the formation of a naked inflorescence stem. This pheno...

BACKGROUND Studies have shown that permissive hypotension for uncontrolled hemorrhagic shock can result in good resuscitation outcome. The ideal target mean arterial pressure (MAP) and the tolerance time for permissive hypotension have not been determined. METHODS To elucidate the ideal target MAP and tolerance time for permissive hypotension with uncontrolled hemorrhagic shock rats, the effe...

OBJECTIVE To compare sexual function before and 12 months after between sacrocolpopexy and sacrocervicopexy. METHODS This retrospective study examined a cohort of 55 sexually active women who underwent either supracervical hysterectomy with sacrocervicopexy (n=28) or total abdominal hysterectomy with sacrocolpopexy (n=27) for stage II to IV pelvic organ prolapse. Pelvic floor support was meas...

Stochasticity ubiquitously inevitably appears at all levels from molecular traits to multicellular, morphological traits. Intrinsic stochasticity in biochemical reactions underlies the typical intercellular distributions of chemical concentrations, e.g., morphogen gradients, which can give rise to stochastic morphogenesis. While the universal statistics and mechanisms underlying the stochastici...

background exertional heat stroke (ehs) is still a main cause of death in sport. many of ehs complications could have been prevented if ehs had been recognized and treated early and properly. case presentation we report an unusual case of multiple organ failure caused by ehs due to intensive sportive activities in a hot environment with lack of primary care. a 35-year-old healthy sportive man w...

background and aims: pelvic organ prolapse (pop) is a common condition which affects on a large proportion of women. the objective of this study was to determine the risk factors of pop in iranian women. methods: this cross-sectional study was carried out to examine the role of demographic, anthropometric and clinical characteristics in pop disease in a sample of 365 females in ilam, iran. exam...