OBJECTIVES/HYPOTHESIS Preservation of the submandibular gland (SMG) during a neck dissection is gaining popularity and is showing an increasing tendency. The potential benefit, if the SMG is preserved, can be manifold. The aim of this study was to assess the benefit of the preservation of the SMG and the associated risk of recurrent disease in patients with oropharyngeal or oral cavity squamous...

A 40-day-old male Holstein breed calf with a complaint of inability of moving the tongue in and out aswell as difficulties with breastfeeding was referred to the veterinary clinic. A notch in the middle of thetongue tip was evident during oral examination. In addition, a thin tissue band between the ventral surface of the tongue and floor of the oral cavity was seen in the calf. A diagnosis of ...

Surgery entails radical resection, neck dissection and tongue reconstruction has been commonly used in treatment of T2 and T3 tongue squamous cell carcinoma. Although lateral upper arm free flap (LUFF) and radial forearm free flap (RFFF) are similar in texture and thickness, significant differences can be noticed in the donor-site function and surgical demands. In the treatment of T2 and T3 ton...

Locoregional lymph nodes metastasis in oral tongue squamous cell carcinoma represents one of important and common prognostic factors for poor clinical outcome. The human Telomerase Reverse Transcriptase (hTERT) is one of key players in cancer metastasis and stemness, but its exact function in tongue squamous cell carcinoma remains unknown. Here, we aim to understand the role of hTERT by utilizi...

to evaluate the effect of adding neoadjuvant chemotherapy to surgery and radiation therapy for locally advanced resectable oral cavity squamous cell carcinoma, 24 patients with t3 or t4a oral cavity squamous cell carcinoma were randomly assigned to surgery alone or docetaxel, cisplatin, and 5-fu (tpf) induction chemotherapy followed by surgery. all patients were planned to receive chemoradiothe...

Introduction: This pilot study compared the effect of tongue cleaning by using a tongue brush alone and the one of combined using a tongue brush and toothbrush. Materials and Methods: 20 healthy young men were studied. The effect of tongue cleaning was assessed according to the following three criteria, including a tongue coating index, H2S concentration and oral bacterial count. These criteria...

  Background and Objectives: Squamous cell carcinoma of the tongue (SCCOT) is the most common malignant neoplasm in oral cavity. At the time of the diagnosis of SCCOT regional metastases with a high mortality rate are common, which is due to the extensive lymphatic system drainage of the tongue. Although the level of healthcare has significantly improved, the survival rate is still low with an...

Oral tongue squamous cell carcinomas (OTSCC) are a homogeneous group of tumors characterized by aggressive behavior, early spread to lymph nodes and a higher rate of regional failure. Additionally, the incidence of OTSCC among younger population (<50yrs) is on the rise; many of whom lack the typical associated risk factors of alcohol and/or tobacco exposure. We present data on single nucleotide...

1 variants and pathways linked to risk habits, HPV, clinical parameters and tumor 2 recurrence 3 4 Neeraja M Krishnan, Saurabh Gupta, Vinayak Palve, Linu Varghese, Swetansu 5 Pattnaik, Prachi Jain, Costerwell Khyriem, Arun K Hariharan, Kunal Dhas, 6 Jayalakshmi Nair, Manisha Pareek, Venkatesh K Prasad, Gangotri Siddappa, 7 Amritha Suresh, Vikram D Kekatpure, Moni Abraham Kuriakose and Binay 8 P...

Metastasis to the head and neck region from primary is rarest manifestation. Lung and breast carcinomas are the commonest malignancies to metastasize to the head and neck region. Oesophageal adenocarcinoma with metastasis to the oral cavity is a rarest presentation and is associated with dismal prognosis. Only few related case reports have been published so far. Her-in we report a case of 55 ye...