The present study aims to examine the efficacy of the natural antimicrobial ε-poly-L-lysine against Streptococcus mutans and against total aerobic oral microflora, alone and in combination with the natural antimicrobial peptide nisin. In in vitro studies, natural antimicrobials nisin A and ε-poly-L-lysine synergized in their action against S. mutans, leading to the microorganism's full inhibiti...

background chlorhexidine gluconate (chx) is the most common antimicrobial agent used against oral pathogens, however information on its ability to inhibit and disrupt anaerobic single and multispecies biofilms is relatively unknown. objectives the purpose of this study was to test the efficacy of chx for its biofilm inhibition and disruption properties using crystal violet assay. materials and ...

background: orthodontic therapy has oral ecological changes causing increased numbers of mutans streptococci in saliva and plaque. the purpose of this study was to estimate counts and colonization pattern of streptococcus mutans after application of fixed orthodontic appliances. materials and methods: plaque samples of randomly selected sixty patients were collected before placement of orthodon...

Oral health, which includes dental is a condition in the oral cavity, teeth and other supporting tissue structures are free from bacteria pain so that they can function optimally. health be maintained by regularly brushing your using toothpaste has an antibacterial effect. Natural ingredients have effect siwak wood mint leaves. Siwak contains salvadorine, shown to on cariogenic such as Streptoc...

Four Gram-positive, catalase-negative, coccoid isolates that were obtained from donkey oral cavities formed two distinct clonal groups when characterized by phenotypic and phylogenetic studies. From the results of biochemical tests, the organisms were tentatively identified as a streptococcal species. Comparative 16S rRNA gene sequencing studies confirmed the organisms to be members of the genu...

BACKGROUND Streptococcus oralis, Streptococcus mitis, and Streptococcus sanguinis are members of the Mitis group of streptococci and agents of oral biofilm, dental plaque and infective endocarditis, disease processes that involve bacteria-bacteria and bacteria-host interactions. Their close relative, the human pathogen S. pneumoniae uses pilus-islet 2 (PI-2)-encoded pili to facilitate adhesion ...

Although the microflora associated with oral mucositis initiated by cytotoxic therapy is not well characterized, several studies suggest that reduction of the microbial load in the oral cavity has some clinical benefit. The MICs of IB-367, a synthetic protegrin analog, ranged from 0.13 to 64 microgram/ml for gram-positive bacteria (Streptococcus mitis, Streptococcus sanguis, Streptococcus saliv...

Cystic fibrosis (CF) patient airways harbour diverse microbial consortia that, in addition to the recognized principal pathogen Pseudomonas aeruginosa, include other bacteria commonly regarded as commensals. The latter include the oral (viridans) streptococci, which recent evidence indicates play an active role during infection of this environmentally diverse niche. As the interactions between ...

BACKGROUND AND PURPOSE Cytotoxic T lymphocyte-induced lysis of virus-infected oral epithelial cells has been shown to be a cause of early ulcer formation in recurrent aphthous ulcerations (RAU). To test whether bacteria and their associated antigens are involved in the disease process of RAU, the proliferative response (PR) to different streptococcal species in peripheral blood mononuclear cell...

BACKGROUND Dental caries is considered to be a preventable disease, and various antimicrobial agents have been developed for the prevention of dental diseases; however, many bacteria show resistance to existing agents. In this study, 14 medicinal herbs were evaluated for antimicrobial activity against five common oral bacteria as a screen for potential candidates for the development of natural ...