organ transplantation is a widely undertaken procedure and has become an important alternative for the treatment of different end-stage organ diseases that previously had a poor prognosis. the field of organ transplant and hematopoietic stem cell transplant is developing rapidly. the increase in the number of transplant recipients also has an impact on oral and dental services. most of the oral...

Oral cancer is a deadly disease. It is often diagnosed late with considerable spread, resulting in a high mortality rate and treatment-associated morbidity. New devices entering the market have stimulated a renewed interest in oral cancer screening among dental professionals. The British Columbia Oral Cancer Prevention Program (BC OCPP) is actively involved in research related to a variety of e...

Adenovirus vectors with E1 deleted of the human serotype 5 (AdHu5) and the chimpanzee serotype 68 (AdC68) expressing the glycoprotein of the Evelyn Rokiniki Abelseth strain of rabies virus were tested upon oral application for induction of systemic and mucosal transgene product-specific antibody responses in mice. Both vectors induced systemic and mucosal antibodies to rabies virus, including v...

The aim of this study was to investigate factors associated with mucosal pain in patients with partial removable dental prostheses (PRDPs). In this hospital-based cross-sectional study, 333 patients wearing 500 PRDPs (mean age 71·4 years, men 33·3%) were consecutively recruited from prosthetic clinic of a dental hospital in Japan. Subjects rated pain intensity and frequency of denture-bearing m...

Oral vaccination offers the advantage of eliciting both a mucosal and a systemic immune response. This study investigated the use of polyacryl starch microparticles as adjuvant for oral vaccination against diphtheria. Diphtheria toxin or cross-reacting material (CRM197) were covalently conjugated to the microparticles and fed to mice by oral gavage. Investigation of formaldehyde treatment as a ...

Background and purpose: The purposes of this study were to analyse the prevalence of oral mucosal lesions with an emphasis on oral regions and possible predictors for their occurrence among removable prosthesis wearers. Materials and methods: The study included 125 removable prosthesis wearers (96 women and 29 men) who were divided into two groups: complete (n=86) and partial (n=39) denture pro...