Understanding the etiology and evolution of the vulnerable coronary plaque is important for the early detection, treatment, and prevention of coronary artery disease. Intravascular optical coherence tomography (OCT) enables imaging of the coronary arteries in vivo with sufficient resolution to accurately differentiate arterial pathology, however, the clinical utility of this technology has been...

Partially coherent illumination provides significant advantages such as speckle-free imaging and enhanced optical sectioning in optical microscopy. The knowledge of the spatial and temporal coherence is crucial to obtain accurate quantitative phase imaging (QPI) of specimens such as live cells, micrometer-sized particles, etc. In this Letter, we propose a novel technique for illumination cohere...

The transfer function for optical wavefront aberrations in single-mode fiber based optical coherence tomography is determined. The loss in measured OCT signal due to optical wavefront aberrations is quantified using Fresnel propagation and the calculation of overlap integrals. A distinction is made between a model for a mirror and a scattering medium model. The model predictions are validated w...

Hand-held OCT systems that offer physicians greater freedom to access imaging sites of interest could be useful for many clinical applications. In this study, by incorporating the theoretical speckle model into the decorrelation function, we have explicitly correlated the crosscorrelation coefficient to the lateral displacement between adjacent A-scans. We used this model to develop and study a...

Quantum optical coherence tomography (QOCT) makes use of an entangled twin-photon light source to carry out axial optical sectioning. We have probed the longitudinal structure of a sample comprising multiple surfaces in a dispersion-cancelled manner while simultaneously measuring the group-velocity dispersion of the interstitial media between the reflecting surfaces. The results of the QOCT exp...

We present an experimental demonstration of quantum optical coherence tomography (QOCT). The technique makes use of an entangled twin-photon light source to carry out axial optical sectioning. QOCT is compared to conventional optical coherence tomography (OCT). The immunity of QOCT to dispersion, as well as a factor of two enhancement in resolution, are experimentally demonstrated. PACS numbers...

An analytical expression for the self coherence function of a microcavity and partially coherent source is derived from first principles in terms of the component self coherence functions. Excellent agreement between the model and experimental measurements of two Resonant Cavity LEDs (RCLEDs) is evident. The variation of coherence length as a function of numerical aperture is also described by ...

Background—A structurally and functionally normal choroidal vasculature is essential for retinal function. Therefore, a precise clinical understanding of choroidal morphology should be important for understanding many retinal and choroidal diseases. Methods—PUBMED (http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed) was used for most of the literature search for this article. The criterion for ...