Zernike polynomials are one of the most widely used mathematical descriptors optical aberrations in fields imaging and adaptive optics. Their orthogonality as well isomorphisms with experimentally observable make them a very powerful tool solving numerous problems beam However, show cross-coupling between individual modes when combination Gaussian beams, an effect that has not been extensively ...

Off-axis monochromatic aberrations in the human eye impose limits on peripheral vision. However, the magnitude of the aberrations off-axis, and in particular coma, has not been yet completely determined. We have developed a procedure to estimate third order aberrations in the periphery of the human eye. The technique is based on recording series of double pass retinal images with unequal entran...

PURPOSE To measure dynamic change characteristics of spatial and temporal variations in the post-blink tear film of normal eyes. METHODS A wavefront sensor was used to measure dynamic changes in wavefront aberrations, up to the seventh order, for 10 seconds in a group of 33 normal young adults. Tear menisci were imaged with an anterior segment optical coherence tomography (AS-OCT) system and ...

In femtosecond laser ophthalmic surgery tissue dissection is achieved by photodisruption based on laser induced optical breakdown. In order to minimize collateral damage to the eye laser surgery systems should be optimized towards the lowest possible energy threshold for photodisruption. However, optical aberrations of the eye and the laser system distort the irradiance distribution from an ide...

Sample-induced image-degradation remains an intricate wave-optical problem in light-sheet microscopy. Here we present biobeam, an open-source software package that enables to simulate operational light-sheet microscopes by combining data from 10–10 multiplexed and GPU-accelerated point-spread-function calculations. The wave-optical nature of these simulations leads to the faithful reproduction ...

Results of recent experimental measurements of aero-optical distortions caused by turbulent boundary layers at subsonic speeds M=0.4..0.6 are presented. Measurements were performed using a high-speed Shack-Hartmann sensor to collect instantaneous wavefronts with high spatial and temporal resolution, accompanied by wavefront measurements with a Malley probe. Effects of different aperture sizes o...

Understanding peripheral optical errors and their impact on vision is important for various applications, e.g. research on myopia development and optical correction of patients with central visual field loss. In this study, we investigated whether correction of higher order aberrations with adaptive optics (AO) improve resolution beyond what is achieved with best peripheral refractive correctio...

PURPOSE Our aim was to obtain a complete description of the interactions of rigid gas permeable (RGP) contact lenses with the optics of normal eyes. METHODS We measured total and anterior-surface aberrations in four subjects, who were all long-term RGP contact lens wearers. The anterior-surface wave aberration was obtained from videokeratographic elevation maps, and ocular wave aberration was...

The main advantage of confocal microscopes over their conventional counterparts is their ability to optically "section" thick specimens; the thin image slices thus obtained can be used to reconstruct three-dimensional images, a capability which is particularly useful in biological applications. However, it is well known that the resolution and optical sectioning ability can be severely degraded...