نتایج جستجو برای: optic nerve head

تعداد نتایج: 353125  

Journal: :Archives of ophthalmology 2002
Elizabeth A Bristow Philip G Griffiths Richard M Andrews Margaret A Johnson Douglas M Turnbull

BACKGROUND The observation of a buildup of mitochondria at the level of the lamina cribrosa in the optic nerve head has traditionally been attributed to axoplasmic stasis. However, this region is also the transition zone for myelination, resulting in differing energy requirements. OBJECTIVE To investigate the relationship between myelination and mitochondrial activity in optic nerve tissue. ...

Journal: :The Journal of Cell Biology 2005
Tatjana C. Jakobs Richard T. Libby Yixin Ben Simon W.M. John Richard H. Masland

Using a variety of double and triple labeling techniques, we have reevaluated the death of retinal neurons in a mouse model of hereditary glaucoma. Cell-specific markers and total neuron counts revealed no cell loss in any retinal neurons other than the ganglion cells. Within the limits of our ability to define cell types, no group of ganglion cells was especially vulnerable or resistant to deg...

Journal: :Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye 2005
Ronit Nesher Ioannis Zacharopoulos Ehud I Assia Joel S Schuman

Careful examination and monitoring of optic nerve head changes is essential in the treatment of patients with glaucoma. This often results in accumulation of numerous photographs and required appropriate storage space. A simple, inexpensive, and efficient means of storing and viewing stereoscopic optic nerve head photographs is described. Images were acquired with a fundus camera, on a color sl...

2014
Kirstin L Tawse Thomas R Hedges Marisa Gobuty Carlos Mendoza-Santiesteban

Optical coherence tomography (OCT) of the macula in patients with primary optic neuropathy has revealed the presence of structural changes in the neurosensory retina in addition to the nerve fibre layer. Subretinal fluid has been documented in papilloedema and non-arteritic ischaemic optic neuropathy, and may account for decreased visual acuity in affected patients. Subretinal fluid has also be...

Journal: :Journal of Medical Case Reports 2008
Timothy A de Klerk David HW Steel

INTRODUCTION The optimum management of a capillary haemangioblastoma affecting the optic nerve head is not clear. A number of treatment modalities have been used to treat the tumours and their consequences. Ocular haemangioblastomas express high levels of vascular endothelial growth factor and levels have been correlated with tumour growth and activity. Treatment with vascular endothelial growt...

2012
Medha V. Wyawahare Pradeep M. Patil Harry A. Quigley Medha Prabhudesai Karen Long Jagdish Nayak Rajendra Acharya P. Subbanna Bhat Nakul Shetty Murray Fingeret Felipe A. Medeiros Remo Susanna Robert N. Weinreb Cristiano Oliveira Allen Chiang Celso Tello Michael Marmor Robert Ritch Jeffrey M. Liebmann Pooja Sharma Pamela A. Sample Linda M. Zangwill Joel S. Schuman Douglas E. Gaasterland Beth Blackwell Leonard G. Dally Joseph Caprioli L. Jay Katz Fred Ederer Michael J. Greaney Douglas C. Hoffman David F. Garway-Heath Mamdouh Nakla Anne L. Coleman P. H. Tomlins R. K. Wang

Glaucoma which is a leading cause of blindness in the world is not a single disease but a group of disorders with diverse clinical manifestations. If not controlled at an early stage, it causes irreversible damage to vision. Proper medication slows down or even halts its growth. Identifying glaucoma at a very early stage is vital and at the same time difficult. Careful evaluation of Optic nerve...

Journal: :Investigative ophthalmology & visual science 2016
Jost B Jonas Yi Dai Songhomitra Panda-Jonas

We thank Jonas and colleagues1 for their interest in our recent paper.2 We agree with the assertion from Jonas and colleagues1 that the biomechanics of the optic nerve dura mater, especially during eye movements, may have strong implications for various structural changes observed in highly myopic eyes. For instance, our models may be able to provide explanations about the optic disc rotation a...

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