Various skeletal dysplas ias known to produce c ranial hyperostosis include osteopetrosis, c rani ometaphyseal dysplas ia, hereditary hyperphosphatasia, Van Buchem disease, and Engelmann disease [1]. Neurologic compl ications such as optic atrophy, facial paralysis, or deafn ess may result from progressive encroachment on the cranial foramina due to bony overgrowth at the base of the skull . Na...

Accurately detection of retinal landmarks, like optic disc, is an important step in the computer aided diagnosis frameworks. This paper presents an efficient method for automatic detection of the optic disc’s center and estimating its boundary. The center and initial diameter of optic disc are estimated by employing an ANN classifier. The ANN classifier employs visual features of vessels and th...

Probe-based confocal laser endomicroscopy (pCLE) is a novel imaging technique which utilizes a low-power laser light passed through a fiber-optic bundle, within a miniprobe that is advanced into the working channel, to obtain microscopic images of the mucosa. This allows the endoscopist to evaluate the microarchitecture of the gastrointestinal epithelium in real time. At this time pCLE cannot r...

McCune-Albright syndrome is a rare fibro-osseous syndrome characterised by a classic triad of fibrous dysplasia (FD), café-au-lait macules and various underlying endocrinopathies. This case report describes how a patient was rediagnosed by a general dental practitioner following attendance for a routine dental examination. The patient had been previously diagnosed with the condition 28 years ea...