A significant interaction between N-methyl-D-aspartate (NMDA) and muscarinic receptors has been suggested in the modulation of learning and memory processes. The present study further investigates this issue and explores whether d-cycloserine (DCS), a partial agonist at the glycine binding site of the NMDA receptors that has been regarded as a cognitive enhancer, would reverse scopolamine (SCOP...

New data on 10 adventive plant species are given. Two and one subspecies (Atriplex hortensis, Solanum nigrum subsp. schultesii, Nepeta cataria) new for the Republic of Buryatia. Five two interspecies hybrids (Arctium × mixtum, Galinsoga parviflora, Hesperis pycnotricha, Lactuca serriola, Medicago varia, Onobrychis viciifolia, Viola tricolor) recorded first time in Ulan-Ude city its neighborhood.

An analysis was performed on 335 pairs of structurally aligned proteins derived from the structural classification of proteins (SCOP http://scop.mrc-lmb.cam.ac.uk/scop/) database. These similarities were divided into analogues, defined as proteins with similar three-dimensional structures (same SCOP fold classification) but generally with different functions and little evidence of a common ance...

SUMMARY MaxBench is a web-based system available for evaluating the results of sequence and structure comparison methods, based on the SCOP protein domain classification. The system makes it easy for developers to both compare the overall performance of their methods to standard algorithms and investigate the results of individual comparisons. AVAILABILITY http://www.sanger.ac.uk/Users/lp1/Ma...

We apply a simple method for aligning protein sequences on the basis of a 3D structure, on a large scale, to the proteins in the scop classification of fold families. This allows us to assess, understand, and improve our automatic method against an objective, manually derived standard, a type of comprehensive evaluation that has not yet been possible for other structural alignment algorithms. O...

In 2021, the author observed and collected Onobrychis caput-galli (L.) Lam., a species of Fabacee previously unknown to Portuguese vascular flora, according Checklist Flora (Sequeira et al., 2011). The was found in Algarve, very restricted area, with several sites occurrence, most which sharing similar habitat conditions. All evidence suggests that is native Portugal should be added flora.

Structural classifications of proteins assume the existence of the fold, which is an intrinsic equivalence class of protein domains. Here, we test in which conditions such an equivalence class is compatible with objective similarity measures. We base our analysis on the transitive property of the equivalence relationship, requiring that similarity of A with B and B with C implies that A and C a...

In the next decades, forage legumes are likely to become more important. However, predicted climate change may increase the risk of droughts and thus influence their agricultural performance. Decreases in yield due to water shortage are well documented, while influences on nutritive values are inconsistent. Therefore, we examined the effects of drought on crude protein (CP), neutral deterge...