A facile and efficient protocol for the synthesis of 1,8-dioxo-octahydroxanthenes has been developed by one-pot Knoevenagel condensation, Michael addition and cyclodehydration reaction of dimedone (active methylene carbonyl compound) with aromatic aldehydes in the presence of Iron (III) sulfate hydrate as a solid acidic catalyst under solvent-free conditions. Various aromatic aldehydes were uti...

A convenient, one-pot method for the synthesis of diazonium salt has been developed by the sequential diazotization of aromatic amines with NaNO2, polymer- supported periodic acid (PPIA) and 2-naphthole under solvent-free conditions at room temperature. By using this method, several types of aromatic amine, containing electron-withdrawing and electron-donating groups, were rapidly converted to ...

A simple, efficient, and high yielding one-pot protocol has been developed for the synthesis of 4H-benzo[b]pyrans scaffolds installing a three-component tandem Knoevenagel-cyclocondensation reaction of an aldehyde, malononitrile and dimedone using guanidinium chloride as polyfunctional organocatalyst under solvent-free conditions in high to excellent yields. Various aromatic aldehydes were util...

A convenient, one-pot method for the synthesis of diazonium salt has been developed by the sequential diazotization of aromatic amines with NaNO2, polymer- supported periodic acid (PPIA) and 2-naphthole under solvent-free conditions at room temperature. By using this method, several types of aromatic amine, containing electron-withdrawing and electron-donating groups, were rapidly converted to ...

Sulfonic acid functionalized SBA-15 (SBA-Pr-SO3H) as a new nanoporous acid catalyst was used in the one-pot synthesis of polyhydroquinolines derivatives via the Hantzsch four component condensation reaction of aldehydes, b-ketoesters, dimedone and ammonium acetate under solvent free conditions with short reaction time in excellent yields. SBA-P...

An efficient and environmental-friendly synthetic route to 1,8-dioxodecahydroacridines derivatives have been developed via multi-component one-pot Hantzsch reaction of various aldehydes and ammonium acetate with 2 equivalents dimedone in the presence of Phosphorus pentoxide supported on aluminaas catalyst under solvent-free conditions. The present approach offersseveral advantages such as short...

A rapid and efficient one-pot, four-component protocol towards the synthesis of polyhydroquinoline derivatives has been developed. The condensation of aldehyde, dimedone, ethyl acetoacetate and ammonium acetate in presence of stannous chloride was carried out under solvent free condition to synthesize a variety of polyhydroquinoline derivatives in good to excellent yields. Stannous chloride was...

A highly efficient and simple protocol for the synthesis of 2-amidoalkylphenols has been described. The one-pot multi-component condensation of phenols with aromatic aldehydes and amides in the presence of catalytic amount of SO3H-functionalized phthalimide (SFP) under solvent-free conditions afford the title compounds in high yields and relatively short reaction times. It is noteworthy that th...

One-pot reaction of aldehydes or ketons with aniline derivatives was performed using NaBH4 and Fe3O4 magnetic nanoparticles (MNPs). The optimum amount of Fe3O4 MNPs was 5 mol% under solvent free condition. The corresponding products were obtained in good to excellent yields. The magnetically recoverable iron oxide nanoparticles are found to be efficient for synthesis of amine derivatives. These...

A highly efficient, simple and clean solvent-free protocol for the synthesis of polyhydroquinolines is described. The one-pot multi-component condensation reaction between arylaldehydes, dimedone (5,5-dimethylcyclohexane-1,3-dione), β-ketoesters and ammonium acetate in the presence of catalytic amount of (2.5 mol%) melamine trisulfonic acid (MTSA) as a recyclable, green and attractive sulfonic ...