This paper reviews the current management of onchocerciasis and its future prospects. Onchocerciasis is a disease affecting millions of people in Africa, South and Central America, and Yemen. It is spread by the blackfly as a vector and caused by the filarial nematode, Onchocerca volvulus. A serious attempt was made by the Onchocerciasis Control Program between 1975 and 2002 to eliminate the ve...

Filariasis The fi larial nematodes Wuchereria bancrofti, Brugia spp., and Onchocerca volvulus are insect-borne parasites that cause lymphatic or cutaneous fi lariasis. Lymphangitis, hydrocele, and elephantiasis are pathologies that result from W. bancrofti and Brugia spp. infections. O. volvulus infections can present with severe skin pathologies (acute and chronic dermatitis, atrophy) and blin...

A deterministic compartmental model for the transmission dynamics of onchocerciasis with nonlinear incidence functions in two interacting populations is studied. The qualitatively analyzed to investigate its local asymptotic behavior respect disease-free and endemic equilibria. It shown, using Routh-Hurwitz criteria, that equilibrium locally asymptotically stable when associated basic reproduct...

he accomplishments of this Programme inspire all of us in public health to dream big dreams. It shows we can reach 'impossible' goals and lighten the burden of millions of the world's poorest people .... " These were the concluding words by former World Health Organization Director-General Gro Harlem Brundtland at the closure ceremony of the Onchocerciasis Control Programme in West Africa (OCP)...

CMAJ • JULY 7, 2009 • 181(1-2) © 2009 Canadian Medical Association or its licensors E4 Although the number of cases of onchocerciasis, commonly known as river blindness, is declining in most of Africa, a worrisome upsurge is being recorded in northern Uganda along the southern Sudan border, where conflict has reigned for most of the last 2 decades. Richard Ndyomugyenyi, head of the Ugandan prog...

Background Onchocerciasis is a serious problem in tropical areas. The role of the parasite as factor associated with neurological diseases needs to be addressed because it might involve reduction risk via elimination strategies. We performed systematic scoping review identify available studies on this association and put into perspective different methodological approaches for interpreting evid...

In June 2020, a door-to-door household survey was conducted in Mvolo County, an onchocerciasis-endemic area South Sudan. A total of 2357 households containing 15,699 individuals agreed to participate the study. Of these, 5046 (32.1%, 95% CI: 31.4–32.9%) had skin itching and 445 (2.8%, 2.6–3.1%) were blind. An epilepsy screening questionnaire identified 813 (5.1%) persons suspected having epilep...