Asparaginase is an enzyme that catalyses the hydrolysis of the amino acid L-asparagine to Laspartic acid and ammonia. The asparaginase enzyme described in the DSM’s dossier is intended for use as a processing aid to reduce in food the levels of free L-asparagine, which is a major precursor in the formation of the food contaminant acrylamide. Acrylamide is formed from Lasparagine and reducing su...

Sugar beet waste has potential value as a soil amendment and this work studied whether fermentation of the waste by Aspergillus niger would influence the growth and P uptake of arbuscular mycorrhizal (AM) fungi. Plants were grown in compartmentalised growth units, each with a root compartment (RC) and two lateral root-free compartments (RFC). One RFC contained untreated soil while the other RFC...

The present study deals with production, extraction and purification of the intracellular and extracellular fungal uricase. The fungal flora will be isolated from soil were (Aspergillua niger, Rhizopus stolonifer, Penicillium chrysogenum and Fusarium moniliforme). Optimization of some nutritional and physical factors in the basal medium in order to intensify the production of extracellular and ...

BACKGROUND The main objective of this study is to establish a benchmark for referral rates in rural Niger so as to allow interpretation of routine referral data to assess the performance of the referral system in Niger. METHODS Strict and controlled application of existing clinical decision trees in a sample of rural health centres allowed the estimation of the corresponding need for and char...

Aspergillus niger forms aerial hyphae and conidiophores after a period of vegetative growth. The hyphae within the mycelium of A. niger are divided by septa. The central pore in these septa allows for cytoplasmic streaming. Here, we studied inter- and intra-compartmental streaming of the reporter protein GFP in A. niger. Expression of the gene encoding nuclear targeted GFP from the gpdA or glaA...

Aspergillus niger is an important microorganism that has been used for decades to produce extracellular enzymes. In this study, a novel Aspergillus niger strain integrated with a eukaryotic expression vector harboring the gpd-Shi promoter of shiitake mushrooms and cellulase gene of Ampullaria gigas Spix was engineered to improve cellulase production for the achievement of highly efficient sacch...

Aim: Hyoscyamus niger (Solanaceae) has been used for treatment of mental disorders, epileptic mania, chronic dementia with insomnia. However, it is not yet studied in condition like depression. The present study was planned with an objective to evaluate its antidepressant like property in animal models of depression and to find out the possible mechanism underlying this action in mouse model of...

BACKGROUND AND AIM Cassia (C.) surattensis Burm. f. (Leguminosae), a medicinal herb native to tropical equatorial Asia, was commonly used in folk medicine to treat various diseases. The aim of the present study is to investigate the effects of methanolic flower extract of C. surattensis against Aspergillus (A.) niger. MATERIALS AND METHODS Antifungal activity of C. surattensis flower extract ...

Onychomycosis is usually caused by dermatophytes, but some species of nondermatophytic molds and yeasts are also associated with nail invasion. Aspergillus niger is a nondermatophytic mold which exists as an opportunistic filamentous fungus in all environments. Here, we report a case of onychomycosis caused by A. niger in a 66-year-old female. The patient presented with a black discoloration an...

Individual and combined effects of aw and incorporation of selected concentrations of Mexican oregano essential oil on the time to growth (TTG) of Aspergillus niger intentionally inoculated into dried tomatoes were studied during storage at 25°C for 100 days. For aw 0.96, 1,000 ppm of Mexican oregano essential oil inhibited A. niger growth during 100 days, whereas 500 ppm were sufficient at aw ...