The existence of the ocular microbiota has been reported but functional analyses to evaluate its significance in regulating ocular immunity are currently lacking. We compared the relative contribution of eye and gut commensals in regulating the ocular susceptibility to Pseudomonas aeruginosa-induced keratitis. We find that in health, the presence of microbiota strengthened the ocular innate imm...

Dry eye is often an under diagnosed condition of the that can cause discomfort, burning sensation and blurred vision. These symptoms are related to alterations in layers tear film, insufficient production or excessive evaporation film. The primary aim this study diagnose find out incidence dry patients presenting with ocular irritation. A total number 225 both sexes aged between 20 80 years com...

Background: Ocular surface health is closely related to the condition of ocular adnexa, particularly eyelids. Both adnexal disorders and oculoplastic procedures performed treat them can cause (OSD). In this review, we aimed summarize relationship between OSD.
 Methods: narrative an electronic search PubMed/MEDLINE database was conducted using various combinations keywords including “oculop...

Background: Spectral-domain optical coherence tomography (OCT) has been used to measure corneal epithelium thickness in dry eye disease, allowing assessment of ocular-surface damage different disease severity. Aim: This study aimed determine the characteristics epithelial with spectral-domain OCT patients and correlate clinical Setting: The was conducted at outpatient clinic Department Ophthalm...

PURPOSE The purpose of this work was to gather preliminary data in normals and dry eye subjects, using a new, non-invasive imaging platform to measure the thickness of pre-corneal tear film. METHODS Human subjects were screened for dry eye and classified as dry or normal. Tear film thickness over the inferior paracentral cornea was measured using laser illumination and a complementary metal-o...

Extensive studies have explored the dynamics of the ocular surface fluid, though theoretical investigations are typically limited to the use of the lubrication approximation, which is not guaranteed to be uniformly valid a-priori throughout the tear meniscus. However, resolving tear film behaviour within the meniscus and especially its apices is required to characterise the flow dynamics where ...

Purpose To investigate the correlation between the changes in the ocular surface temperature (OST) and tear film stability over soft contact lenses (SCLs). Methods We enrolled 20 eyes of 20 normal SCL wearers (20 men; 24.4 ± 4.1 years). We used four different daily disposable SCLs: one silicone hydrogel lens (delefilcon A) and three hydrogel lenses (etafilcon A with polyvinylpyrrolidone [PVP]...

In Parkinson's disease (PD) patients, a wide range of ocular and visual disorders are present. Tear film instability, inflammation dysfunction the surface, presence symptoms disturbance characterize dry eye, multifactorial surface. Based on literature search, we discuss frequency, pathogenesis, influence quality life patients with eye in disease. Furthermore, review available means diagnosis ma...

PURPOSE To assess the expression of human leucocyte antigen (HLA)-DR in epithelial cells and cluster of differentiation (CD8)-positive lymphocytes as possible markers of chronic ocular graft versus host disease (cGvHD) after hematological stem cell transplantation (HSCT). METHODS Twenty-seven consecutive patients with dry-eye symptoms following HSCT (24 [89%] with peripheral blood stem cell t...

PurposeTo evaluate the effects of chalazion excision on ocular surface, taking into account subjective symptoms and objective parameters tear film.MethodsThis prospective, interventional clinical study included 52 eyes from 26 patients with eyelid who underwent lesions between March August 2022. Chalazion was performed patient's eye, contralateral eye served as control. The following were inves...