نتایج جستجو برای: octahydro 9 ethyoxy 10 hydroxy 1 anthracenone
تعداد نتایج: 3524412 فیلتر نتایج به سال:
Advanced small cell lung cancer (SCLC) has a dismal prognosis. Modulation of the camptothecin topotecan, approved for second-line therapy, may improve response. Our recent finding of synergistic enhancement of the cytotoxic activity of camptothecin (CPT) by cyclin-dependent kinase 4 inhibitors is extended here to a panel of camptothecin analogs comprising 10-hydroxy-CPT (HOCPT), topotecan (TPT;...
In highly social bees, queen mandibular pheromone (QMP) is vital for colony life. Both Apis cerana (Ac) and Apis mellifera (Am) share an evolutionarily conserved set of QMP compounds: (E)-9-oxodec-2-enoic acid (9-ODA), (E)-9-hydroxydec-2-enoic acid (9-HDA), (E)-10-hydroxy-dec-2-enoic acid (10-HDA), 10-hydroxy-decanoic acid (10-HDAA), and methyl p-hydroxybenzoate (HOB) found at similar levels. H...
an efficient synthesis of the 1,l'-dihydroxy-2,2'-(thiodimethy1ene)bis-9(10h)- anthrone (5) is described. reaction of 1 -methoxy-2-(bromomethy1)-9,loanthraquinone (1) with excess sodium sulfide in ethanol, demethylation to the corresponding hydroxy and subsequent selective reduction produced the title compound in high yield.
The voltage-gated KV7 (KCNQ) potassium channels are activated by ischemia and involved in hypoxic vasodilatation. We investigated the effect of KV7 channel modulation on cardiac ischemia and reperfusion injury and its interaction with cardioprotection by ischemic preconditioning (IPC). Reverse-transcription polymerase chain reaction revealed expression of KV7.1, KV7.4, and KV7.5 in the left ant...
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