OBJECTIVES To evaluate the associations between maternal age and obstetric and neonatal outcomes in primiparous women with emphasis on teenagers and older women. DESIGN A population-based cohort study. SETTING The Swedish Medical Birth Register. PARTICIPANTS Primiparous women with singleton births from 1992 through 2010 (N=798,674) were divided into seven age groups: <17 years, 17-19 year...

BACKGROUND In many developing countries vitamin K prophylaxis is not routinely administered at birth. There are insufficient data to assess the cost effectiveness of its implementation in such countries. OBJECTIVE To estimate the burden of intracranial haemorrhage caused by late onset vitamin K deficiency bleeding in Hanoi, Vietnam. METHODS Cases of intracranial haemorrhage in infants aged ...

The pharmaceutical industry’s business model is hefty investment in research and development (R&D), in expectation of high returns from future drug sales during the period of patent protection. This model, which funds around 50% of health care R&D in the United States and a higher proportion in Europe [1], generates 20–25 new licensed drugs per year, but very few for use in pregnancy. After tha...

OBJECTIVE To identify risk factors for preterm delivery in women with placenta praevia and antepartum haemorrhage. DESIGN Retrospective study. SETTING Regional obstetric unit, Hong Kong. SUBJECTS AND METHODS Women delivered at Princess Margaret Hospital between 1 January 1990 and 31 December 1997. Possible risk factors for preterm delivery among women with placenta praevia and antepartum ...

AIMS To determine the frequency with which myometrium is removed during vacuum terminations of pregnancy or dilatation and curettage after miscarriage, and to relate these findings to subsequent placenta accreta or its proxies. METHODS Archival tissues from vacuum termination of pregnancy or dilatation and blunt curettage after miscarriage were examined for the presence of myometrium. The sub...

ObjectiveTo explore diagnoses of postpartum haemorrhage following vaginal birth, in relation to socio-demographic and obstetrical data from women who gave birth at term, Sweden, during the years 2005–2015.Study designA register-based cohort study was carried out, describing comparing variables, obstetric variables infant 52 367 cases diagnosed compared 353 569 controls without a diagnosis. Post...

OBJECTIVE To quantify the burden of maternal and neonatal conditions in low- and middle-income countries (LMICs) that could be averted by full access to quality first-level obstetric surgical procedures. DESIGN Burden of disease and epidemiological modelling. SETTING LMICs from all global regions. POPULATION The entire population in 2010. METHODS We included five conditions in our analy...

A demographic study carried out in a rural area of the Gambia between January 1993 and December 1998 recorded 74 deaths among women aged 15-49 years. Reported here is an estimation of maternal mortality among these 74 deaths based on a survey of reproductive age mortality, which identified 18 maternal deaths by verbal autopsy. Over the same period there were 4245 live births in the study area, ...