Ni2+ supported on hydroxyapatite-core@shell γ-Fe2O3 nanoparticles (γ-Fe2O3@HAp-Ni2+) was found to be a useful catalyst for the synthesis of benzimidazole derivatives from o-phenylenediamine and aldehydes under solvent and solvent-free conditions at 80 °C. This reaction affords the corresponding benzimidazole derivatives compared with the classical reactions this method consistently gives a high...

An efficient and green protocol for the synthesis of 2-arylsubstituted benzimidazoles via a condensation reaction of aromatic aldehydes and 1,2-phenylenediamine using nano-Fe3O4@SiO2-SO3H as a solid acid catalyst in ethanol under reflux conditions has been described. The reactions are completed in short times, and the corresponding benzimidaz...

Poly (o-Phenylenediamine) and its ZnO nanocomposites were synthesized at different concentrations metal oxide like 5%, 10% and 15% of ZnO by via chemical oxidative polymerization method using ammonium persulphate as an oxidant in the presence of HCl. The prepared polymer and its polymer nanocomposites are found to be soluble in common organic solvents like ethanol, DMSO, toluene etc. The format...

Reports that globular proteins could enhance the interference blocking ability of the PPD (poly(o-phenylenediamine) layer used as a permselective barrier in biosensor design, prompted this study where a variety of modifying agents were incorporated into PPD during its electrosynthesis on Pt-Ir electrodes. Trapped molecules, including fibrous proteins and β-cyclodextrin, altered the polymer/modi...

Optimum reaction conditions were evaluated for assay of serum ceruloplasmm by measurement of its p-phenylenediamine oxidase activity. The pH optima of p-phenylenediamine oxidase activities of human and rat ceruloplasmins were 5.45 and 5.2, respectively. The p-phenylenediamine oxidase activity of rat ceruloplasmin was markedly inhibited by phosphate (0.1 mol/Iiter), that of human ceruloplasmin o...

Imidazole and phenyl rings are fused at positions 4 5 to form the benzimidazole structure. The mono- disubstituted derivatives extremely intriguing heterocyclic chemical compounds. They can be synthesized using a straightforward condensation method between o-phenylenediamine carbonyl compound under various conditions as well nucleophilic substitution reaction. catalytical effects of derivatives...

have been structurally characterized, relatively few free Schiff bases have been similarly characterized.1 N-Substituted salicylaldimines show photochromism and thermochromism in the solid state. These effects are produced by intramolecular proton transfer associated with a change in the π-electron configuration.2 As part of a general study of tetradentate Schiff bases, we determined the struct...

In the context of our systematic investigations of pentaand hexacoordinate silicon compounds, which included dianionic tri(O,N,O1; O,N,N1) and tetradentate (O,N,N,O; O,N,N1,O1) chelators, we have now explored silicon coordination chemistry with a dianionic tetradentate (N,N1,N1,N) chelator. The ligand [o-phenylene-bis(pyrrole-2-carbaldimine), H2L] was obtained by condensation of o-phenylenediam...

The aerobic respiratory chain of Escherichia coli is branched. In aerobically grown cells harvested in midexponential phase, a respiratory chain containing only b-type cytochromes is predominant. This chain contains a terminal oxidase which is a b-type cytochrome, referred to as cytochrome o. However, when the bacteria are grown under conditions of oxygen limitation, additional components of th...

The ability of 51 compounds, of known carcinogenic potential, to induce "unscheduled DNA synthesis" in HeLa cells has been tested in the presence or absence of a rat liver mixed-function oxidase preparation. Chemicals tested included those giving erroneous results in bacterial mutagenicity assays as well as representative compounds from various classes of chemical carcinogens including nitrosam...