the thiosemicarbazides 3a-c were appeared by reaction of the corresponding substituted hydrazides 1a-c with allylisothiocyanate 2. synthesis of some novel 1,2,4-triazole-thiols 4a-c bearing a pyridyl unit using 1-(x-picolinoyl)-4-allyl-thiosemicarbazides (x = 2,3,4) in an alkaline solution, is reported. also, the s-alkylation of triazole derivatives 5-7a-c is described. the structure of the syn...

an action resulting from an object like human's damaging action can cause liability for those who possess them. the french civil law at its approval time (1804) had not predicted this principle and just in articles 1385, 1386, the liability of damages resulting from two types of objects, i.e. animals and buildings due to imposing great damages by them had been predicted by french law. howe...

background: memory impairment is a well-known effect of many benzodiazepine compounds which is mediated through their action on gamma-aminobutyric acid type a (gabaa) receptors. on the other hand, cannabinoids can affect learning and memory process through presynaptic modulation of the release of both excitatory glutamate and inhibitory gaba transmitters in brain regions involved in learning an...

epilepsy is one of the common neurologic disorders in children. drug side-effects are one of the important problems in treating patients with epilepsy. using the antiepileptic medication may cause different side effects such as disorder in bone and vitamin d metabolism. sodium valproate is one of the antiepileptic medications used widely. some of its side effects include digestive disorder, inc...

the present experiment was conducted to determine nutritional values of wild pistachio trees (p. khinjuk) leaves it's use it in the diet of sheep. initially chemical composition of p. khinjuk leaf was determined. the diets containing 0, 5, 10, 15, 20, 25 and 30% of p. khinjuk leaf were prepared and used for sheep to determine the best replacement level of it with corn silage. fermentation ...

in this study, precipitated calcium carbonate (pcc) was modified using cationic starch, and its effect on optical and physical properties of paper was examined in comparison with unmodified filler afterwards. to determine the filler retention in paper, both modified and unmodified fillers were added to pulp suspensions by 20, 30, and 40 percentages. for comparing the utilization effect of modif...

to study the effects of biofertilizers on physiological and morphological characteristics, as well on essential oil content in dragonhead (dracocephalum moldavica), an experiment was conducted at tarbiat modares university in 2009. the studied factors were: vermicompost (0, 15, 30% v/pot), azotobacter (inoculated and non-inoculated), and phosphatic biofertilizer (inoculated and non-inoculated)....

the catalytic air oxidation-trimerization of alcohols was carried out with hetropolyacids. in the presence of hetropolyacid formation of cyclotrimers of alcohols and aldol condensation products was observed. the 1,3,5-trioxanes were major and aldol condensation compounds were minor products.

it is widely thought that bcl-2 family proteins regulate commitment to apoptosis primarily through their capacity to control the permeability of the mitochondrial outer membrane permeabilization (momp) triggers the release of multiple apoptogenic factors into the cytosol and, thereby apoptosis. various bcl-2 family members affect this key event of the apoptotic cascade in different ways, determ...