The mol-ecular structure of the title compound, C(15)H(15)NO, involves an intra-molecular C-H⋯O hydrogen bond. The central amide group -NH-C(=O)- is twisted by 37.95 (12)° out of the meta-substituted benzoyl ring and by 37.88 (12)° out of the ortho-substituted aniline ring. The two benzene rings are inclined to one another at only 4.2 (1)° having an inter-planar spacing of ca 0.90 Å. The crysta...

Abstract Novel l ‐tartaric acid based stereodynamic biphenylbisphosphinite ligands with anilino linkers were prepared as cyclic diamide compounds. The influence of the constitutional substitution pattern amino group at aniline moiety on diastereoselective formation ligand was investigated. While meta ‐anilino bridged showed a highly dynamic behavior and no discrimination between ( R ax ) S conf...

The carcinogen aniline is negative in the Ames Salmonella mutagenicity assay. Aniline does, however, induce intrachromosomal recombination between repeated sequences in Saccharomyces cerevisiae, resulting in deletion (DEL) of intervening sequences. We have investigated whether the generation of oxidative free radical species by aniline and/ or its metabolites may be responsible for its recombin...

We investigated the effects of trace element deficiency on drug-metabolizing enzymes in rats. Weanling rats were fed a selenium-deficient diet (Torula yeast) or a normal diet (0.5μg selenium) until 20 weeks. After six weeks of the selenium-deficient diet, an increase in aniline hydroxylase activity was observed in the selenium-deficient rats, but the activity of aminopyrine N-demethylase was re...

an ion imprinted polymer (iip) based on aniline-formaldehyde was synthesized and then modified with extra aniline as cross-linker in the presence and absence of sr (ii) as the template to produce ion imprinted poly(aniline-formaldehyde) (iipaf) and non imprinted poly(aniline-formaldehyde) (nipaf). the sorbent was characterized by fourier transform infrared spectroscopy and was used for solid ph...

The room temperature ionic liquid (IL) 1-butyl-3-methylimidazolium bis-(trifluorometanesulfonyl)imide BMIm[NTf₂] was used as a novel medium for improvement of separation and quantization of 16 aromatic amines typically present as contaminants in consumer products and detected by HPLC coupled to an electrochemical detector. The aromatic amines, namely 4,4'-diaminodiphenylmethane, 4-chloroaniline...

A simple and efficient one-pot, three-component Strecker reaction of protected amino acids, aromatic aldehydes, and trimethylsilyl cyanide has been developed for the synthesis of chiral α-amino nitriles. The reaction was carried out in the presence of catalytic amount of phosphotungstic acid (H3[P(W3O10)4]) as an environmentally friendly cata...

Enhancement of aniline hydroxylation by Habu snake venom was studied in vitro. The fraction which was isolated from Habu venom through column chromatography caused the enhancement of aniline hydroxylation of hepatic microsomes obtained from untreated rats. This fraction was heat stable and free from phospholipase activity. Enhancement of aniline hydroxylation was not clear in crude Habu venom o...

The interactions of aniline with soil at an industrial spill site were investigated. Sorption of aniline to the soil was observed to occur through a two-step mechanism. The first step was an ion exchange process with the protonated amine serving as an organic cation. This step was influenced by solution pH and ionic composition. The second step was covalent bonding most likely with quinone moie...

We have developed a new technology called multi-catalysis for the sequential one-pot synthesis of highly functionalized heterocycles. A practical and novel multi-component aniline-, self- and Brønsted acid-catalyzed selective process for the sequential one-pot synthesis of highly substituted 2-(2-hydroxy-aryl)-cyclopentane-1,3-diones, 3,9-dihydro-2H-cyclopenta[b]chromen-1-ones and 3,3-dimethyl-...