10" Phenotypic plasticity, the ability for a single genotype to generate different phenotypes in 11" response to environmental conditions, is biological ubiquitous and yet almost nothing is 12" known of the developmental mechanisms that regulate the extent of a plastic response. In 13" particular, it is unclear why some traits or individuals are highly sensitive to an 14" environmental variable...

The parameter of weight/height ratio as a percentage of the 50th percentile is a basic measure for nutritional status in pediatric oncology and measures adequately response to therapeutic intervention.

DNA methylation was reported as a possible stress-adaptation mechanism involved in the transcriptional regulation of stress responsive genes. Limited data are available on effects of psychological stress and early-life nutritional stress on DNA methylation regulators [DNMTs: DNA (cytosine-5)-methyltransferase 1 (DNMT1), DNMT1 associated protein (DMAP1), DNMT 3 alpha (DNMT3A) and beta (DNMT3B)] ...

background free radicals are known as atoms and molecules which are highly reactive with the body’s single-electrons, and may cause irrecoverable damages to the macromolecules of organisms. systems to deal with damages caused by free radicals are known as “antioxidant immune systems”. flavonoids and polyphenolic compounds are from non-enzymatic antioxidants which many nutritional compounds cont...

malnutrition and inflammation are the most important causes of cardiovascular disease in hemodialysis patients. this study was conducted to evaluate the effect of increase in hemodialysis frequency on c-reactive protein (crp) level and nutritional markers in contrast to previous routine method. 18 hemodialysis patients with a mean age of 53±16 years were randomly selected in this before-and-aft...

Nutritional intervention in the cancer patient [e.g., total parenteral nutrition (TPN)] might improve durable survival because of increased tolerance to aggressive tumor therapy. To determine whether this assumption is correct, 42 patients with diffuse histiocytic lymphoma were induced with prednisone, high-dose methotrexate, Adriamycin, cyclophosphamide, and VP-16 (ProMACE). Nitrogen mustard-v...

silver carp is the major specimen in warm water fish culture system in iran which is presented in various size and different price. the present study was aimed to compare nutritional value and to investigate proportion of nutritional value and financial of various weight groups of silver carp in spring season. for this purpose silver carp was prepared in market sizes and their dry matter, fat, ...

OBJECTIVE Procalcitonin is useful for the diagnosis of sepsis, but its prognostic value regarding mortality is unclear. Our objective was to determine the prognostic value of procalcitonin determined at the onset of sepsis, and to compare it with other markers of inflammatory response, malnutrition and organ dysfunction data. METHODS We studied 253 hospitalized patients (146 men, 107 women) w...

AIMS Insulin-like growth factor 1 (IGF-1) is known to exert cardioprotective actions. However, it remains unknown if autophagy, a major adaptive response to nutritional stress, contributes to IGF-1-mediated cardioprotection. METHODS AND RESULTS We subjected cultured neonatal rat cardiomyocytes, as well as live mice, to nutritional stress and assessed cell death and autophagic rates. Nutrition...

INTRODUCTION Sepsis is one of the main causes of mortality in patients in Intensive Care Units. As a result of the systemic inflammatory response and of the decrease of the aerobic metabolism in sepsis, the oxidative stress occurs. Vitamin A is recognized by the favorable effect that it exerts on the immune response to infections and antioxidant action. OBJECTIVE To bring new elements for rev...