We and others have established that the developmental Notch receptor signaling pathway is active in breast cancer cell lines, as well as in preinvasive and invasive primary samples. Recently, a role for Notch in regulating the hierarchy of stem and progenitor cells in both normal and cancer epithelium has been elucidated. Because inhibiting the Notch receptor signaling pathway is a possible fut...

This study outlines the recent developments in metal forming processes, focusing mainly on shearing process. A summary of background process is given to give perspective how such a has changed over time. It explains what operations are and operated forming. While also outlining difference between shearing, slitting, punching, notching, blanking advantages disadvantages detailed. Different types...

introduction : open rhinoplasty is very common now a days and the number of candidate for this type of surgery are increasing. this research was conducted regarding to the prevalence of rhinoplasty surgery , the importance of the residual scar analyze including columellar scar after surgery, different results caused by the effect of incision type in this surgery and lack of enough data and expe...

BACKGROUND Early designs of reverse shoulder arthroplasty components for the treatment of glenohumeral arthritis associated with severe rotator cuff deficiency in some cases have been associated with mechanical failure. The purpose of this study was to perform a prospective outcomes study of reverse shoulder arthroplasty performed with use of 5.0-mm peripheral locking screws for baseplate fixat...