نتایج جستجو برای: normal tissue complication probability
تعداد نتایج: 1618256 فیلتر نتایج به سال:
PurposeIn the Netherlands, head and neck cancer (HNC) patients are selected for proton therapy (PT) based on estimated normal tissue complication probability differences (?NTCP) between photons protons, which requires a plan comparison (VMAT vs. IMPT). We aimed to develop tools improve patient selection comparisons.MethodsThis prospective study consisted of 141 consecutive in was done. IMPT pla...
PURPOSE Current normal tissue complication probability modeling using logistic regression suffers from bias and high uncertainty in the presence of highly correlated radiation therapy (RT) dose data. This hinders robust estimates of dose-response associations and, hence, optimal normal tissue-sparing strategies from being elucidated. Using functional data analysis (FDA) to reduce the dimensiona...
PURPOSE To examine the feasibility of volumetric modulated arc therapy (VMAT) for post mastectomy radiotherapy (PMRT). METHODS AND MATERIALS Fifteen PMRT patients previously treated at our clinic with helical tomotherapy (HT) were identified for the study. Planning target volumes (PTV) included the chest wall and regional lymph nodes. A systematic approach to constructing VMAT that met the cl...
Abstract Background Immediate breast reconstruction with tissue expander in cancer patients who were expected to receive adjuvant therapy, such as chemotherapy or radiotherapy, has been a topic of debate. Postoperative complications from procedures can delay the timing treatment and subsequently increase probability recurrence. The purpose this study was identify impact radiotherapy on postoper...
Modern radiotherapy technologies such as proton beam therapy (PBT) permit dose escalation to the tumour and minimize unnecessary doses to normal tissues. To achieve appropriate patient selection for PBT, a normal tissue complication probability (NTCP) model can be applied to estimate the risk of treatment-related toxicity relative to X-ray therapy (XRT). A methodology for estimating the differe...
AIMS AND BACKGROUND Conventional radiotherapy in inoperable cholangiocarcinoma is limited by radiotolerance of the surrounding tissues. The aim of our dosimetric study was an evaluation of intensity-modulated radiotherapy in the treatment of inoperable bile duct carcinoma. METHODS Four patients with inoperable cholangiocarcinoma treated by self-expandable stent placed to the biliary tree and ...
PURPOSE Lung cancer radiotherapy treatments employ a wide variety of fractionation protocols. The choice among protocols mostly depends on the size of the target volume (GTV or ITV) and the volume of normal tissue receiving a critical dose. Rigorous mathematical criteria for normal tissue (NT) dose distributions were derived to determine the type of dose per fraction schedule that maximizes lin...
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