TO THE EDITOR: We read the article by Tse et al. 1 with interest , which showed the usefulness of 12-item General Health Questionnaire (GHQ-12) as a reliable screening tool for psychiatric disorders in the patients with functional dyspepsia. Interesting studies were recently published showed anxiety to be linked to functional dyspepsia and especially postprandial distress syndrome, but not epig...

This study aims to determine whether the features of dyspepsia can discriminate a subgroup of patients who present with non-ulcer dyspepsia from other diagnostic categories. The following groups were studied: One hundred and thirteen patients with endoscopically confirmed non-ulcer dyspepsia in the absence of clinical, biochemical or radiological evidence of other gastrointestinal diseases or d...

ackground & Aims: The aim of this study was to ssess systematically the efficacy of proton pump inhibtors (PPIs) in the treatment of functional dyspepsia ompared with placebo and to determine if any differnce in the response exists between symptom subgroups f functional dyspepsia. Methods: A literature search as performed through September 2005 in PubMed, Medine, Embase, CINAHL, and Cochrane da...

BACKGROUND Helicobacter pylori eradication therapy is routinely used for treating patients with peptic ulcer disease. AIMS To assess the value of symptomatic response to H pylori eradication therapy as a marker of post-treatment H pylori status. PATIENTS AND METHODS One hundred and nine dyspeptic patients with active duodenal or gastric ulceration association with H pylori infection had the...

OBJECTIVES To verify whether symptoms reported by patients with uninvestigated dyspepsia might be helpful in either classifying functional from organic dyspepsia (1st experiment), or recognising which Helicobacter pylori infected patients may benefit from eradication therapy (2nd experiment). METHODS We compared the performance of artificial neural networks and linear discriminant analysis in...

BACKGROUND & AIMS The aim of this study was to assess systematically the efficacy of proton pump inhibitors (PPIs) in the treatment of functional dyspepsia compared with placebo and to determine if any difference in the response exists between symptom subgroups of functional dyspepsia. METHODS A literature search was performed through September 2005 in PubMed, Medline, Embase, CINAHL, and Coc...

Due to its prevalence, impact on quality-of-life and the associated significant health resource utilization, dyspepsia is a major healthcare concern. The available management strategies for uninvestigated dyspepsia include prompt endoscopy, the 'test-and-treat' strategy for Helicobacter pylori, and empiric antisecretory therapy. There is consensus that endoscopy should be reserved for patients ...