Somers and Shive (37) suggested that the physiological availability of iron in plants is determined by the relative manganese supply and that the optimum growth and yield of plants depend on a certain definite proportion rather than the absolute level of iron and manganese supply. These workers also held that iron deficiency is identical with manganese excess and iron excess with manganese defi...

Data on 16 patients with uremia are presented. The cerebral blood flow was moderately decreased in patients with generalized vascular disease, but was normal in patients with minimal vascular involvement. In both groups the cerebral oxygen consumption (cerebral metabolic rate in terms of oxygen consumption, CAIRO,) was reduced significantly and to the same degree. In contrast, total body metabo...

The presence of nonprotein α-dialkyl-amino acids such as α-aminoisobutyric acid (α-AIB) and isovaline (Iva), which are considered to be relatively rare in the terrestrial biosphere, has long been used as an indication of the indigeneity of meteoritic amino acids. However, recent work showing the presence of α-AIB and Iva in peptides produced by a widespread group of filamentous fungi indicates ...

Eighteen cases of disseminated lupus erythematosus were verified by postmortem study in a series of 19,242 autopsies. Shortness of breath was the most common complaint and occurred in 16. Fourteen of this number had definite cardiac pathology. All 16 had definite pulmonary pathology. Fourteen cases had abnormal urinalysis. Of these cases, 7 had elevated blood nonprotein nitrogen values of over ...

Electical potentials across the membrane in a modified AutoAnalyzer dialyzer (Technicon) have been determined under various conditions and related to the dialysis of 45Ca. The results suggest that anomalies in the diffusion of calcium from protein and nonprotein containing streams could be due to factors other than "Donnan equilibrium effects."

The objective of this research was to examine the effect of high concentrations of nonprotein nitrogen (NPN) on the voluntary food intake of sheep fed high-quality grasses. Wether lambs (n = 6 per treatment) were fed dried switchgrass (Panicum virgatum L.; Exp. 1) or dried tall fescue (Festuca arundinacea Schreb.; Exp. 2). In both experiments, urea was added to the dried forage at 0 (control), ...

Crude extracts of tentacles of two polychaetous annelids completely inhibit growth of Erlich ascites tumor in 60 to 100 percent of treated mice. Dialyzed extracts of one of these annelids, Lanice conchilega, show activity in the retentate after pronase digestion, suggesting that antitumor activity is associated with a nonprotein component of the crude tentacle extract.

The application of stable isotope analysis to ecology requires estimating the contribution of different isotopic sources to the isotopic signatures of an animal's tissues using mixing models. These models make the physiologically unrealistic assumption that assimilated nutrients are disassembled into their elemental components and that these atoms are then reassembled into biomolecules. We quan...

BACKGROUND The appropriate caloric goal for critically ill adults is unclear. We evaluated the effect of restriction of nonprotein calories (permissive underfeeding), as compared with standard enteral feeding, on 90-day mortality among critically ill adults, with maintenance of the full recommended amount of protein in both groups. METHODS At seven centers, we randomly assigned 894 critically...

An improved chemically defined basal medium (CMRL-1415) has been used to advantage in studying the effects on trypsinized, newly explanted mouse embryo cells of certain glycoproteins from plasma and serum, certain nonprotein macromolecules, and various combinations of these, in stationary cultures. When protein and nonprotein fractions were separated from fetal calf serum, the entire growth act...