BACKGROUND Despite strong evidence for beta-blockers and angiotensin-converting enzyme inhibitors (ACEI) or angiotensin receptor blockers (ARB) in chronic heart failure (CHF), they have been under-utilised especially in general medical units. We aim to evaluate the effectiveness and feasibility of a physician-targeted quality improvement intervention with education and feedback on the prescript...

BACKGROUND Beta-blockers refer to a mixed group of drugs with diverse pharmacodynamic and pharmacokinetic properties. They have shown long-term beneficial effects on mortality and cardiovascular disease (CVD) when used in people with heart failure or acute myocardial infarction. Beta-blockers were thought to have similar beneficial effects when used as first-line therapy for hypertension. Howev...

Beta adrenergic blockers have been one of the most prescribed category of drugs during the past 15 years. Recently, many new beta blockers have been introduced because they have unique pharmacokinetic and pharmacodynamic properties that benefit patients. The purpose of this article is to review the pharmacological properties and clinical uses of beta blockers. The latter part of this review wil...

Heart failure (HF), chronic obstructive pulmonary disease (COPD), and asthma are considered as major health problems. They affect 1-3%, 4-10%, and 8-19% of population, respectively, and frequently coexist. Pulmonary function testing and echocardiography are needed for reliable diagnosis, but in clinical practice, diagnosis often is based on history and disease self-reporting. Concomitant HF can...

Beta-blockers are the cornerstone of treatment for various cardiovascular conditions. were discovered as antianginal drugs in 1960s and currently widely used heart failure, arrhythmias, ischemic disease. In this article, we review evidence beneficial effects beta-blockers these conditions, well current recommendations clinical practice guidelines their use. Surprisingly, despite having been pre...

OBJECTIVES This study was designed to examine the effects of carvedilol in a murine model of viral myocarditis induced by encephalomyocarditis virus (EMCV) infection. BACKGROUND Cytokines play an important role in the pathophysiology of viral myocarditis. Catecholamines influence the production of cytokines via beta-adrenergic receptors, suggesting that beta-adrenergic blockers could modulate...