introduction: different environmental factors such as drugs, ionizing radiation, etc can induce apoptosis.in the present study the effects of dose- rate and post-irradiation incubation time on gamma radiation inducedapoptosis in human breast carcinoma cell line (t-47d) (invasive ductal carcinoma) was investigated. material and methods: the t-47d cells were cultured in t25 flasks and during log ...

We study the radiation-driven warping of accretion discs in the context of X-ray binaries. The latest evolutionary equations are adopted, which extend the classical alpha theory to time-dependent thin discs with non-linear warps. We also develop accurate, analytical expressions for the tidal torque and the radiation torque, including self-shadowing. We investigate the possible non-linear dynami...

OBJECTIVES To investigate the accuracy and scientific validity of the current very low risk factor for hereditary diseases in humans following exposures to ionizing radiation adopted by the United Nations Scientific Committee on the Effects of Atomic Radiation and the International Commission on Radiological Protection. The value is based on experiments on mice due to reportedly absent effects ...

The biological effects of high charge and energy (HZE) particle exposures are of interest in space radiation protection of astronauts and cosmonauts, and estimating secondary cancer risks for patients undergoing Hadron therapy for primary cancers. The large number of particles types and energies that makeup primary or secondary radiation in HZE particle exposures precludes tumor induction studi...

The prediction of entropy generation with a thermal and exponential space dependent heat source unsteady flow over rotating disk is the artifact paper. For specific physical model, non-Newtonian fluids like Oldroyd-B within EMHD fluid encrypted. Also, mechanism cobalt tantalum nanoparticles in blood employed. proper self-similarity variables are used to convert non-linear PDE system equations i...

This paper presents a review of several studies conducted in our laboratory to examine the carcinogenic effects in mice of high-LET radiation and, for comparison, of low-LET reference radiation. For some specific end-points the following conclusions can be formulated: i) the dose-response curves for myeloid leukemia and malignant lymphoma can be interpreted in terms of induction and inactivatio...

Photostress has to be considered during optical micromanipulation of gametes. Ultraviolet light, including low-energy UVA (32-400 nm) radiation, as well as high-intensity near infrared (NIR) laser radiation may induce cell damage. A total number of 580 light-exposed sperm cells were studied in single-cell photostress experiments. Low-power (1.5 mW, 5.3 W/cm2) UVA exposure with 365 nm radiation ...

background: radiation-induced lung injury is a refractory side effect in lung cancer radiotherapy, the mechanism still remains unclear, hence an appropriate animal mode may become useful to investigate it. materials and methods: 50 female wistar rats were randomly divided into 5 groups, average 10 rats/cage: a. control group b. 3gy×10f c. 6gy×5f d. 12.5gy×1f e.15.3gy×1f. by different doses of r...

Research reports using cells from bacteria, yeast, alga, nematodes, fish, plants, insects, amphibians, birds and mammals, including wild deer, rodents or humans show non-linear radio-adaptive processes in response to low doses of low LET radiation. Low doses increased cellular DNA double-strand break repair capacity, reduced the risk of cell death, reduced radiation or chemically-induced chromo...

Radiation therapy achieves its therapeutic effects by inducing apoptosis and non-apoptotic cell death. The aim of this focused review is to highlight the aspects of the cell death pathways most relevant to conventional fractionated radiation therapy. I review reports on how our current understanding of the molecular mechanisms of cell death may enable us to revise the four radiobiological princ...