Ionizing radiation is known to induce numerous effects in cells including cell cycle delay, DNA damage, altered gene expression and cell death. Although there are serious impacts on the organisms, the effects on prenatal development are largely unknown. Data regarding potential biological effects on the prenatal development after in utero radiation exposure predominantly stem from atomic bomb s...

Exposure of cells to ionizing radiation leads to formation of reactive oxygen species (ROS) that are associated with radiation-induced cytotoxicity. Therefore, compounds that scavenge ROS may confer radioprotective effects. Recently, it has been shown that the decomposition product of the spin-trapping agent alpha-phenyl-N-t-butylnitrone (PBN), N-t-butyl hydroxylamine (NtBHA), mimics PBN and is...

OBJECTIVE To observe the protective effects of puerarin on radiation injury of experimental rats and to discuss the possible mechanism of its radiation protection. METHODS Wistar rats were divided randomly into 4 groups with 8 rats in each group: physiological saline non-radiation (SN) group, puerarin non-radiation (PN) group, physiological saline radiation (SR) group, puerarin radiation (PR)...

A wide variety of biological effects are induced in cells that are exposed to ionizing radiation. The expression changes of coding mRNA and non-coding micro-RNA have been implicated in irradiated cells. The involvement of other classes of non-coding RNAs (ncRNA), such as small nucleolar RNAs (snoRNAs), long ncRNAs (lncRNAs), and PIWI-interacting RNAs (piRNAs) in cells recovering from radiation-...

Current and future trends in functional neuroimaging focus on the combination and synchronous application of imaging modalities by integrating more than one measures of brain function, e.g., hemodynamic and electrophysiological (EEG and fMRI). These multimodal approaches aim at achieving sufficient temporal and spatial resolution in order to localize neural activity and identify the functional ...

The linear no-threshold (LNT) model of ionizing-radiation-induced cancer is based on the assumption that every radiation dose increment constitutes increased cancer risk for humans. The risk is hypothesized to increase linearly as the total dose increases. While this model is the basis for radiation safety regulations, its scientific validity has been questioned and debated for many decades. Th...

The aim of this preliminary investigation was to assess whether human peripheral blood lymphocytes which have been pre-exposed to non-ionizing radiofrequency fields exhibit an adaptive response (AR) by resisting the induction of genetic damage from subsequent exposure to ionizing radiation. Peripheral blood lymphocytes from four healthy donors were stimulated with phytohemagglutinin for 24 h an...

background: after radiation therapy (rt), some health hazards including dna damages may occur where melatonin can play a protective role due to free radical generation. on the other hand, serious accidental overexposures may occur during rt due to nuclear accidents which necessitate the need for study on exposure to high-dose radiations during treatments. objective: the aim of this study was to...

Due to the non-linear ionizing and heating processes, 21-cm signals from epoch of reionization (EoR) are expected have strong non-Gaussian fluctuations. In this paper, we use semi-numerical simulations study statistics i.e. skew spectrum smoothed skewness EoR. We find similar evolution features with bispectrum. All them sensitive EoR models, while not too much cosmic volume applied. With SKA1-l...

ABSTRACT Observations of reionization-era analogues at z ? 3 are a powerful tool for constraining reionization. Rest-ultraviolet observations particularly useful, in which both direct and indirect tracers ionizing-photon production escape can be observed. We analyse sample 124 galaxies from the Keck Lyman Continuum Spectroscopic Survey, with sensitive spectroscopic measurements continuum region...