this paper presents a methodology for design of instrumentation sensor networks in non-linear chemical plants. the method utilizes a robust extended kalman filter approach to provide an efficient dynamic data reconciliation. a weighted objective function has been introduced to enable the designer to incorporate each individual process variable with its own operational importance. to enhance the...

this paper aims to investigate the integrated production/distribution and inventory planning for perishable products with fixed life time in the constant condition of storage throughout a two-echelon supply chain by integrating producers and distributors. this problem arises from real environment in which multi-plant with multi-function lines produce multi-perishable products with fixed life ti...

conclusions in the chinese han population that we studied, nafld patients who carry the tnf-α-238 ga polymorphism have an increased risk of developing cad. mechanisms underlying this potentially important association require further investigation. background cardiovascular events account for the main cause of death in patients with non-alcoholic fatty liver disease (nafld), and are largely infl...

the rs2476601 (r620w, c1858t) polymorphism in ptpn22 gene has been repeatedly reported to be associated with rheumatoid arthritis (ra). the rs 2476601 is widely suggested for predictive testing and risk assessment for ra. the aim of this study was to test the possible association of this snp with ra in iranian population.a total of 872 samples (405 confirmed ra patients and 467 healthy controls...

in this study, a two-objective mixed-integer linear programming model (milp) for multi-product re-entrant flow shop scheduling problem has been designed. as a result, two objectives are considered. one of them is maximization of the production rate and the other is the minimization of processing time. the system has m stations and can process several products in a moment. the re-entrant flow sho...