the clinical and economic importance of heart failure is widely recognized.   the incidence of heart failure is on the increase, particularly with the aging of the population around the world.   it is time for a paradigm shift in heart failure management. alternative non-pharmacological strategies to remodel the failing ventricle will shape a major portion of heart failure therapy in the decade...

BACKGROUND Inhibitors of hyaluronidase are potent agents that maintain hyaluronic acid homeostasis and may serve as anti-aging, anti-inflammatory, and anti-microbial agents. Sodium copper chlorophyllin complex is being used therapeutically as a component in anti-aging cosmeceuticals, and has been shown to have anti-hyaluronidase activity. In this study we evaluated various commercial lots of so...

– We study the effect of shear on the aging dynamics of a colloidal suspension of synthetic clay particles. We find that a shear of amplitude γ reduces the relaxation time measured just after the cessation of shear by a factor exp(−γ/γc), with γc ∼ 5%. From this rejuvenation effect, we extract a quantitative strain/temperature correspondence between colloidal systems and molecular or spin glass...

Aging is a time-dependent decline in physiological function that affects most organisms and the major risk factor for many non-communicable diseases. The early diagnosis of aging critical treatment aging-related In recent years, extensive efforts have attempted to accurately diagnose aging. To date, multiple types fluorescent probes various age-related biomarkers been developed, with aims achie...

   Nowadays, in addition to materials and components of asphalt mixtures that are bitumen, aggregates and mineral fillers, other materials known as additives or modifiers are also used. These compounds include wide range of organic, inorganic, industrial, and natural materials used in order to reduce deficiencies, to improve the physical properties and to modify some mechanical properties o...

The work presented has been carried out to obtain a better insight into electrical aging phenomena of mica insulation as used in high voltage rotating machines. Model bars with typical insulating materials were exposed to standard electrical aging and stimulated tree propagation at a new electrode arrangement. The results show that time to breakdown under electrical load is mainly determined by...

PURPOSE Stiffening of the arteries results in increased pulse-wave velocity (PWV), the propagation velocity of the blood. Elevated aortic PWV has been shown to correlate with aging and atherosclerotic alterations. We extended a previous non-triggered projection-based cardiovascular MR method and demonstrate its feasibility by mapping the PWV of the aortic arch, thoraco-abdominal aorta and iliof...