BACKGROUND Noise induced hearing loss (NIHL) is a major preventable occupational health hazard. OBJECTIVE To measure permanent threshold shift in traffic police personnel due to noise exposure and to examine whether it was associated with duration of noise exposure, years of work and risk factors. METHODS Cross sectional, descriptive study conducted at Dhulikhel hospital, Kathmandu Universi...

Age-related and noise-induced hearing losses in humans are multifactorial, with contributions from, and potential interactions among, numerous variables that can shape final outcome. A recent retrospective clinical study suggests an age-noise interaction that exacerbates age-related hearing loss in previously noise-damaged ears (Gates et al., 2000). Here, we address the issue in an animal model...

Problem statement: Noise Induced Hearing Loss (NIHL) is one of the most important occupational disease in worldwide. NIHL has been found to be potentiated by simultaneous Carbon monoxide (CO) exposure. Exposure to noise plus CO is common in occupational and environmental settings. Free radicals have been implicated in cochlear damage resulting from exposure to noise and due to CO hypoxia This s...

background hearing capability plays a principal role on human's communication. noise-induced hearing loss (nihl) caused by exposure to high noise levels is a serious socio-economic problem in modern societies. nihl can either be reversible, resulting in a temporary threshold shifts (tts) or irreversible, resulting in a permanent threshold shifts (pts). pts is often confirmed in the time span of...

PURPOSE Iatrogenic noise produced by mastoid or craniotomy drills may cause hearing damage, which is induced by the generation of reactive oxygen species (ROS) and the reduction of cochlear blood flow (CoBF). This study investigated whether propofol could reduce noise-induced hearing loss (NIHL) in a guinea pig model. METHODS Sixty-four male pigmented guinea pigs were randomly and equally div...

Noninvasive low-level laser therapy (LLLT) is neuroprotective, but the mechanism of this effect is not fully understood. In this study, the use of LLLT as a novel treatment for noise-induced hearing loss (NIHL) is investigated. Sprague-Dawley rats were exposed to intense noise and their right ears were irradiated with an 808nm diode laser at an output power density of 110 or 165mW/cm(2) for a 3...

Previous research has suggested that farmers are at increased risk for noise-induced hearing loss (NIHL) due to excessive amounts of loud noise exposure from farming equipment. This study was conducted to determine the perceived effects of hearing loss in a small farming population. Ninety-three subjects, ranging in age from 18 to 75 years and actively engaged in the farming industry, were aske...

Isl1 is a LIM-homeodomain transcription factor that is critical in the development and differentiation of multiple tissues. In the mouse inner ear, Isl1 is expressed in the prosensory region of otocyst, in young hair cells and supporting cells, and is no longer expressed in postnatal auditory hair cells. To evaluate how continuous Isl1 expression in postnatal hair cells affects hair cell develo...

OBJECTIVE Bilateral audiometric notch (BN) at 4000-6000 Hz was identified as a noise-induced hearing loss (NIHL) phenotype for genetic association analysis in college-aged musicians. This study analysed BN in a sample of US youth. DESIGN Prevalence of the BN within the study sample was determined and logistic-regression analyses were performed to identify audiologic and other demographic fact...