نتایج جستجو برای: nicotinic acetylcholine receptor

تعداد نتایج: 607747  

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2013
Irina Esterlis Jonas O Hannestad Frederic Bois R Andrew Sewell Rachel F Tyndale John P Seibyl Marina R Picciotto Marc Laruelle Richard E Carson Kelly P Cosgrove

UNLABELLED In vivo estimation of β(2)-nicotinic acetylcholine receptor availability with molecular neuroimaging is complicated by competition between the endogenous neurotransmitter acetylcholine and the radioligand (123)I-3-[2(S)-2-azetidinylmethoxy]pyridine ((123)I-5-IA). We examined whether binding of (123)I-5-IA is sensitive to increases in extracellular levels of acetylcholine in humans, a...

Journal: :Proceedings for Annual Meeting of The Japanese Pharmacological Society 2021

Journal: :The Journal of pharmacology and experimental therapeutics 1997
W R Kem V M Mahnir R L Papke C J Lingle

We assessed the pharmacological activity of anabaseine, a toxin found in certain animal venoms, relative to nicotine and anabasine on a variety of vertebrate nicotinic receptors, using cultured cells, the Xenopus oocyte expression system, contractility assays with skeletal and smooth muscle strips containing nicotinic receptors and in vivo rat prostration assay involving direct injection into t...

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