Terlipressin is a synthetic long-acting analog of vasopressin widely used to control variceal bleeding by lowering portal venous pressure. We report an unusual adverse reaction to terlipressin in a 78-year-old patient with esophageal variceal bleeding who developed skin necrosis soon after treatment initiation. Skin biopsy revealed embolia cutis medicamentosa.

Livedoid vasculopathy is a skin disease that occludes the blood vessels of the dermis. It has a pauciinflammatory or non-inflammatory nature. It is characterized by the presence of macular or papular, erythematous-purpuric lesions affecting the legs, especially the ankles and feet, and producing intensely painful ulcerations, which cause white atrophic scars called "atrophie blanche". This revi...

Livedo vasculopathy (LV) is a chronic cutaneous disorder characterised by recurrent, painful ulceration ending in stellate scars. We have conducted a retrospective study of clinical features and treatment response of LV in 24 Chinese patients. LV occurred more frequently in women (male:female ratio  1:3). The peak age at onset of disease ranged from 14 to 20 years, younger than previously publi...

Dear Editor, I read with interest the article titled “Acute central retinal artery occlusion associated with livedoid vasculopathy: a variant of Sneddon’s syndrome [1] and there may be a different diagnosis. Since a few cases of young patients have been identified with Susac syndrome with livedo, could this case represent a case of this disorder? Did the patient have an magnetic resonance imagi...

We prove in the setting of \(Q\)-Ahlfors regular PI-spaces following result: if a domain has uniformly large boundary when measured with respect to \(s\)-dimensional Hausdorff content, then its visible \(t\)-dimensional content for every \(0<t<s\leq Q-1\). The is set points that can be reached by John curve from fixed point \(z_{0}\in \Omega\). This generalizes recent results Koskela-Nand...

A proposta, neste artigo, é de investigar a leitura que John Pocock faz do republicanismo Nicolau Maquiavel. Neste sentido, dois são os argumentos principais deste trabalho. Em primeiro lugar, trata-se evidenciar se, um lado, Maquiavel recupera o ideal aristotélico humano como animal político, outro tal se passaria modo transformá-lo numa versão enfraquecida, à medida em radicalmente impactada ...