Although Nogo-A has been intensively studied for its inhibitory effect on axonal regeneration in the adult central nervous system, little is known about its function during brain development. In the embryonic mouse cortex, Nogo-A is expressed by radial precursor/glial cells and by tangentially migrating as well as postmigratory neurons. We studied radially migrating neuroblasts in wild-type and...

background: recurrent herpes labialis (rhl) is one of most common infective vesiculoulcerative lesions. according to some studies administration of topical and/or systemic zinc compositions has been effective in treatment and prevention. this article aims to comparison of zinc level in healthy subjects and rhl patients in acute and convalescent phases. materials and methods: this was a retrospe...

Unraveling the causes underlying Alzheimer's disease (AD) is certainly one of the greatest challenges of this century for researchers. With advances in medicine and technology, the world is experiencing a demographic shift towards a growing elderly population. With this increasingly ageing population, the number of individuals being affected by AD is booming. AD has a significant negative impac...

Cerebral vascular disease is very common in the elderly and is one of the most dangerous diseases which is hazardous to the body's health, and it is the medical specialists' study hot spot not only in the clinical field but also in the medical basic research field. Neural regeneration has been paid more and more attention in recent years. Nogo's function in the process of neural regeneration ha...

BACKGROUND Glucose variability could be an independent risk factor for diabetes complications in addition to average glucose. The deficiency in islet β cell secretion and insulin sensitivity, the two important pathophysiological mechanisms of diabetes, are responsible for glycemic disorders. The oral disposition index evaluated by product of insulin secretion and sensitivity is a useful marker ...