Pulmonary hypertension results in an increased afterload for the right ventricle (RV). To determine the effects of this increased afterload on RV contractile performance, we examined RV performance before and during 4 h of partial balloon occlusion of the pulmonary artery and again after releasing the occlusion in nine newborn lambs. RV contractile performance was quantified by indexes derived ...

Nearly 40 potassium channels have been described in respiratory epithelial cells. Of these are found several members of the 4-transmembrane domain, 2-pore K(+) channel family (K2P family), namely Twik-1 and -2, Trek-1 and -2, Task-2, -3, and -4, Thik-1, and KCNK7. The aim of this study was to verify whether the Twik-related acid-sensitive K(+) channel, subtype 1 (Task-1) (also known as KCNK3), ...

Bupivacaine is frequently administered to produce analgesia during labor and can be shown to be present in the neonate, indicating that bupivacaine crosses the placenta. Neurobehavioral studies have been unable to detect any effect upon the neonate of bupivacaine. This study looks specifically at the changes in laryneal chemo(L.C.R.) and diving(D.R.) reflex responses in newborn lambs. Stimulati...

This thesis presents three main contributions in the context of modeling and simulation of physiological systems. The first one is a formalization of the methodology involved in multiformalism and multi-resolution modeling. The second one is the presentation and improvement of a modeling and simulation framework integrating a range of tools that help the definition, analysis, usage and sharing ...

Data of 5,390 Merino lambs born from 1986 to 2007 (approximately 6.9 generations) were used to derive genetic parameters and trends for age-specific and overall lamb survival on the underlying scale, as well as for lamb birth weight, using Gibbs sampling. The majority of lambs were descended from lines that were divergently selected for the ability of ewes to rear multiples. The line selected i...

This paper deals with the study of the spectral components of Lamb waves generated in thin aluminium plate using pulsed Nd-YAG laser and detected using a He-Ne Laser Heterodyne interferometer. Laser generation of Lamb waves leads to simultaneous generation of various frequency component as well as multiple Lamb wave modes. The Lamb wave signals are successfully and comprehensively analyzed usin...

In this study 71 head of conceiving ewe and their progeny (91 head) from the flock of Lori-Bakhtiari sheep (360 head), in Sholi Station were randomly selected to determine the relationship between the immunoglobulin (IgG) concentration in the ewe's serum and colostrum, and lamb's serum. Ewe blood sample, colostrum of ewe and blood of the lamb was taken 2 weeks before parturition, 1 to 8 hours a...

To investigate the contribution of LamB in Klebsiella pneumoniae antimicrobial resistance, we determined the MICs of various antibiotics and the frequency of mutation to increased cefoxitin or meropenem resistance of the strains CSUB10S (expressing only OmpK36), CSUB10R (lacking OmpK35 and OmpK36), and their derived isogenic insertion-duplication mutants deficient in LamB. Expression of LamB wa...