نتایج جستجو برای: neuronal death

تعداد نتایج: 382959  

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2000
W J Friedman

Nerve growth factor (NGF) and related neurotrophins influence neuronal survival and differentiation via interactions with the trk family of receptors. Recent studies have demonstrated that neurotrophins may also induce cell death via the p75 receptor. The importance and generality of neurotrophin-induced death in the brain have not been defined but may play a critical role during development an...

2017
Kee-Oh Chay Kyoung Young Nam Koong Shinae Hwang Jong-Keun Kim Choon Sang Bae

β-Amyloid peptide (Aβ) is the main component of senile plaques in patients with Alzheimer's disease, and is known to be a main pathogenic factor of the disease. Recent evidence indicates that activation of NADPH oxidase (NOX) in microglia or astrocytes may be a source of Aβ-induced reactive oxygen species (ROS). We investigated the role of neuronal NOX in Aβ-induced neuronal death in mouse mixe...

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