OBJECTIVES This study examined the performance of percent aggregate plaque volume (%APV), which represents cumulative plaque volume as a function of total vessel volume, by coronary computed tomography angiography (CTA) for identification of ischemic lesions of intermediate stenosis severity. BACKGROUND Coronary lesions of intermediate stenosis demonstrate significant rates of ischemia. Coron...

In this paper, the problem of guaranteed cost fault-tolerant control for networked control systems (NCSs) is discussed based on Lyapunov stability theory and Linear Matrix Inequality (LMI). The sufficient conditions possessing robust integrity against actuator failures are given by adopting memory state feedback control law, which can meet a cost function for closed-loop networked control syste...

Analysis of the system design principles of signaling systems requires model systems where all components and regulatory interactions are known. Components of the Lac and Ntr systems were used to construct genetic circuits that display toggle switch or oscillatory behavior. Both devices contain an "activator module" consisting of a modified glnA promoter with lac operators, driving the expressi...

OBJECTIVES To determine, based on clinical criteria, the proportion of multiple sclerosis (MS) patients responsive to immunomodulators (RI) and nonresponsive to immunomodulators (NRI), and to ascertain whether clinical and epidemiological data differs between RI and NRI patient groups. METHODS Patients were assessed on rate of exarcerbations per year, for the period before and after commencem...

BACKGROUND Artificial neural network (ANN)-based bone scan index (BSI), a marker of the amount of bone metastasis, has been shown to enhance diagnostic accuracy and reproducibility but is potentially affected by training databases. The aims of this study were to revise the software using a large number of Japanese databases and to validate its diagnostic accuracy compared with the original Swed...

Naturally occurring defective interfering RNAs (DI-RNAs) and satellite RNAs greatly reduce the accumulation of their helper virus in vivo, but often modulate symptom expression in an unpredictable manner. Deletion mutants Nc/S, Na/M and Sa/Nc + M/S, derived from brome mosaic virus (BMV) RNA-2, failed to replicate when co-inoculated with BMV RNAs-1 and -2 to barley protoplasts. However, the inoc...

background: concept of e-readiness is used in many areas such as e-business, e-commerce, e-government, and e-banking. in terms of healthcare, e-readiness is a rather new concept, and is propounded under the title of e-healthcare. e-health readiness refers to the readiness of communities and healthcare institutions for the expected changes brought by programs related to information and communica...

This paper presents an extended discussion of issues associated with the role of information privacy in IS research. This discussion was initiated in conjunction with a panel session at ICIS 2002. Following the conference, each of the panelists reworked and extended their position statements, and provided a commentary on the position statements of the other panelists. The paper is framed with h...

conclusions herein we have described the stata package “adpredsurv” for calculation of the nam-d’agostino x2 goodness of fit test as well as cut point-free and cut point-based nri, relative and absolute idi, and survival-based regression analyses. we hope this work encourages the use of novel methods in examining predictive capacity of the emerging plethora of novel biomarkers. background a fun...

The scientific problem in our project is defined as a question: how social technologies could contribute to the development of smart and inclusive society? The subject of our research are networked projects (virtual CI systems) which include collective decision making tools and innovation mechanisms allowing and encouraging individual and team creativity, entrepreneurship, online collaboration,...